Results 181 to 190 of about 466,886 (231)

SIRT3 alleviates painful diabetic neuropathy by mediating the FoxO3a-PINK1-Parkin signaling pathway to activate mitophagy. [PDF]

open access: yesCNS Neurosci Ther
Yang J   +11 more
europepmc   +1 more source

The Treatment of Painful Diabetic Neuropathy

Current Diabetes Reviews, 2022
:Painful diabetic peripheral neuropathy (painful-DPN) is a highly prevalent and disabling condition, affecting up to one-third of patients with diabetes. This condition can have a profound impact resulting in a poor quality of life, disruption of employment, impaired sleep, and poor mental health with an excess of depression and anxiety. The management
Gordon Sloan   +2 more
exaly   +3 more sources

Management of painful diabetic neuropathy

open access: yesExpert Opinion on Pharmacotherapy, 2008
The commonest cause of peripheral neuropathy is diabetes and pain occurs in approximately 30% of diabetic patients with neuropathy. It is extremely distressing for the patient and poses significant difficulties in management, as no treatment to date provides total relief and the side effects of therapy limit dose titration.
Tavakoli, Mitra, Malik, Rayaz A
openaire   +5 more sources

Pathophysiology and treatment of painful diabetic neuropathy

open access: yesCurrent Pain and Headache Reports, 2008
Diabetes is the most common cause of peripheral neuropathy, and painful diabetic neuropathy (PDN) affects approximately 30% of diabetic patients with neuropathy. It is extremely distressing for the patient and poses significant management difficulties because no treatment provides total relief, and side effects of therapy are a major limiting factor ...
Tavakoli, Mitra   +3 more
openaire   +4 more sources

Painful diabetic neuropathy

Best Practice & Research Clinical Endocrinology & Metabolism, 1999
Chronic painful diabetic neuropathy can cause a variety of challenges, particularly in successful treatment. The pain, which can last for years, can severely impair quality of life. Management is difficult, although the careful use of drugs can be significantly beneficial.
S J, Benbow, I A, MacFarlane
openaire   +4 more sources

Painful Diabetic Neuropathy

Clinics in Podiatric Medicine and Surgery, 2008
The podiatric physician often encounters complex painful neuropathies in daily practice. Diabetic neuropathy is one form of chronic neuropathic pain dealt with on a regular basis. The goal of this article is to review the pathophysiology, diagnosis, and treatment options of this complaint.
Rhonda S, Cornell, Ivica, Ducic
openaire   +2 more sources

Diabetic neuropathies and pain

Clinics in Endocrinology and Metabolism, 1986
Many of the diabetic neuropathic syndromes are characterized by painful symptoms with a sensation of burning and associated with troublesome hyperaesthesia. It is important to distinguish between the acute and chronic forms of peripheral sensory neuropathy; while the former carries an excellent prognosis for symptomatic improvement within one year, the
A J, Boulton, J D, Ward
openaire   +2 more sources

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