Results 51 to 60 of about 677,940 (286)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
SOCIAL BONDING: REGULATION BY NEUROPEPTIDES
Frontiers in Neuroscience, 2014 Affiliative social relationships (e.g., among spouses, family members, and friends) play an essential role in human society. These relationships affect psychological, physiological, and behavioral functions.
Claudia eLieberwirth, Zuoxin eWang
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Frontiers in NeuroscienceIntroductionThe mesolimbic reward system is associated with the promotion and rewarding benefits of social relationships. In the socially monogamous prairie vole (Microtus ochrogaster), the establishment of a pair bond can be displayed by a robust ...
Kyle Richard Gossman +6 more
doaj +1 more source
UV-induced modification of fused silica: Insights from ReaxFF-based molecular dynamics simulations
AIP Advances, 2016 Atomic structural modification and defect processes of fused silica resulting from UV-laser irradiation are studied by a combination of molecular dynamics (MD) simulations and the Reactive Force Field (ReaxFF).
Ye Tian +5 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Beyond Human Intentions and Emotions
Frontiers in Human Neuroscience, 2013 Although significant advances have been made in our understanding of the neural basis of action observation and intention understanding in the last few decades by studies demonstrating the involvement of a specific brain network (action observation ...
Elsa eJuan +5 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Persistent effects of pair bonding in lung cancer cell growth in monogamous Peromyscus californicus
eLife, 2021 Epidemiological evidence suggests that social interactions and especially bonding between couples influence tumorigenesis, yet whether this is due to lifestyle changes, homogamy (likelihood of individuals to marry people of similar health), or directly ...
Asieh Naderi +5 more
doaj +1 more source
The Additivity of the Energies of Normal Covalent Bonds [PDF]
, 1932 The chemical bond between two identical atoms, as in the molecules H2, Cl2, etc., may be considered as an example of a normal covalent bond, involving an electron pair shared by the two atoms.
Pauling, Linus, Yost, Don M.
core