Intraclass Correlation in Paired Associative Stimulation and Metaplasticity. [PDF]
Paired associative stimulation (PAS) is a widely used noninvasive brain stimulation protocol to assess neural plasticity. Its reproducibility, however, has been rarely tested and with mixed results.
Schapira G +9 more
europepmc +2 more sources
A new index of cortical plasticity induced by paired associative stimulation to describe cognitive status in aged healthy subjects. [PDF]
IntroductionCortical plasticity is a key factor for cognitive skills, and paired associative stimulation (PAS) is useful to study it in humans. Currently, due to the number of non-responders to PAS and discrepancies in the post-PAS time-points assessed ...
Loi N +8 more
europepmc +2 more sources
Promoting motor recovery after stroke using cortico-cortical paired associative stimulation. [PDF]
Summary: Stroke is the most prevalent neurological disorder, the primary cause of long-term disability, and the second leading cause of mortality. Post-stroke motor symptoms critically impact and limit stroke survivors’ quality of life.
Falaschi D, Stagg C, Sel A.
europepmc +2 more sources
Investigating the Intervention Parameters of Endogenous Paired Associative Stimulation (ePAS). [PDF]
Advances in our understanding of neural plasticity have prompted the emergence of neuromodulatory interventions, which modulate corticomotor excitability (CME) and hold potential for accelerating stroke recovery. Endogenous paired associative stimulation
Alder G +6 more
europepmc +2 more sources
Paired associative stimulation improves motor function in the upper extremity in chronic incomplete spinal cord injury: a corroborative study. [PDF]
Objective: To corroborate findings suggesting that spinally targeted paired associative stimulation improves upper extremity motor function in chronic incomplete spinal cord injury. Design: Prospective interventional study.
Wahlgren C, Levi R, Thordstein M.
europepmc +2 more sources
Gradual enhancement of corticomotor excitability during cortico-cortical paired associative stimulation. [PDF]
Cortico-cortical paired associative stimulation (ccPAS) is an effective transcranial magnetic stimulation (TMS) method for inducing associative plasticity between interconnected brain areas in humans.
Turrini S +5 more
europepmc +2 more sources
Paired associative stimulation improves outcomes when applied at the subacute stage after incomplete cervical spinal cord injury. [PDF]
We conducted a randomized sham-controlled clinical trial from 2019 to 2024 to characterize the safety and efficacy of applying paired-associative stimulation (PAS), consisting of high-intensity transcranial magnetic stimulation and high-frequency ...
Shulga A +8 more
europepmc +2 more sources
Motor Cortical Correlates of Paired Associative Stimulation Induced Plasticity: A TMS-EEG Study. [PDF]
Paired associative stimulation (PAS) is a non-invasive brain stimulation technique that modulates synaptic plasticity in the human motor cortex (M1). Since previous studies have primarily used motor-evoked potentials (MEPs) as outcome measure, cortical ...
Costanzo M +9 more
europepmc +2 more sources
Motor Point Stimulation in Spinal Paired Associative Stimulation can Facilitate Spinal Cord Excitability. [PDF]
Paired associative stimulation at the spinal cord (spinal PAS) has been shown to increase muscle force and dexterity by strengthening the corticomuscular connection, through spike timing dependent plasticity. Typically, transcranial magnetic stimulation (
Fok KL +5 more
europepmc +2 more sources
A Methodological Evaluation of Four Different Paired Associative Stimulation Paradigms in Healthy Controls. [PDF]
Background/Objectives: Plasticity deficits play a key role in the pathophysiology of various psychiatric and neurological disorders. Paired associative stimulation (PAS) leverages Hebbian principles to induce synaptic plasticity in the human brain.
Hodzic K +4 more
europepmc +2 more sources

