Results 41 to 50 of about 671,694 (290)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Failure of the Point Blinding Countermeasure Against Fault Attack in Pairing-Based Cryptography
Pairings are mathematical tools that have been proven to be very useful in the construction of many cryptographic protocols. Some of these protocols are suitable for implementation on power constrained devices such as smart cards or smartphone which are ...
Nadia El Mrabet, Emmanuel Fouotsa
semanticscholar +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Efficient Anonymous Certificateless Multi-Receiver Signcryption Scheme Without Bilinear Pairings
Certificateless multi-receiver encryption/signcryption (CLME/CLMS) has become a research hotspot in the field of information security. Almost all of the existing CLME/CLMS schemes are constructed based on the bilinear pairing computation, a time ...
Liaojun Pang +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Computational and Energy Costs of Cryptographic Algorithms on Handheld Devices
Networks are evolving toward a ubiquitous model in which heterogeneous devices are interconnected. Cryptographic algorithms are required for developing security solutions that protect network activity. However, the computational and energy limitations of
Helena Rifà-Pous +1 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Pairing Optimizations for Isogeny-Based Cryptosystems
In isogeny-based cryptography, bilinear pairings are regarded as a powerful tool in various applications, including key compression, public key validation, and torsion basis generation. However, in most isogeny-based protocols, the performance of pairing
Shiping Cai, Kaizhan Lin, Chang-An Zhao
doaj +1 more source
An Enhancement of the Elliptic Curve Cryptography by Using the PairingFunction
In this paper, we propose two new algorithms to increase the security of the Elliptic Curve Cryptography (ECC) by using a pairing function. The two algorithms are based on using two pairing functions, which are the Cantor pairing function and the Elegant
Sarah Hatem Namous +2 more
doaj +1 more source

