Results 41 to 50 of about 23,346,457 (282)

Fast AVX-512 Implementation of the Optimal Ate Pairing on BLS12-381

Transactions on Cryptographic Hardware and Embedded Systems
Non-degenerate bilinear maps on elliptic curves, commonly referred to as pairings, have many applications including short signature schemes, zero-knowledge proofs and remote attestation protocols.
Hao Cheng, Georgios Fotiadis, Johann Großschädl, Daniel Page   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Using Abelian Varieties to Improve Pairing-Based Cryptography [PDF]

Journal of Cryptology, 2008
In this long and quite technical paper the authors study several aspects of Pairing-Based Cryptography. Bilinear pairings (Weil and Tate pairings) on elliptic curves or higher dimensional abelian varieties are used in Cryptography both in a constructive and destructive way, see [Handbook of elliptic and hyperelliptic curve cryptography. Boca Raton, FL:
Karl Rubin, Alice Silverberg
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

On the Security of Certificateless Signature Schemes

International Journal of Distributed Sensor Networks, 2013
Wireless Sensor Network (WSN) has proved its presence in various real time applications and hence the security of such embedded devices is a vital issue. Certificateless cryptography is one of the recent paradigms to provide security.
Gaurav Sharma, Suman Bala, Anil K. Verma
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Pairing Optimizations for Isogeny-Based Cryptosystems

IET Information Security
In isogeny-based cryptography, bilinear pairings are regarded as a powerful tool in various applications, including key compression, public key validation, and torsion basis generation. However, in most isogeny-based protocols, the performance of pairing
Shiping Cai, Kaizhan Lin, Chang-An Zhao
doaj   +1 more source