Results 151 to 160 of about 22,968 (195)

Author Correction: O-GlcNAcylation of MITF regulates its activity and CDK4/6 inhibitor resistance in breast cancer. [PDF]

Nat Commun
Zhang Y, Zhou S, Kai Y, Zhang YQ, Peng C, Li Z, Mughal MJ, Julie B, Zheng X, Ma J, Ma CX, Shen M, Hall MD, Li S, Zhu W.   +14 more
europepmc   +1 more source

Genome-wide CRISPR screen identified NEK6 as a determinant of sensitivity to CDK4/6 inhibitor in endometrial cancer. [PDF]

Front Pharmacol
Jian F, Zhu C, Wang Y, Zhou T, Yang C, Feng W.   +5 more
europepmc   +1 more source

Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trials [PDF]

, 2017
et al,, Mutch, David G
core   +1 more source

Management of Severe Abemaciclib-induced Liver Dysfunction: Feasibility of Switching to Palbociclib. [PDF]

In Vivo
Takada S, Umehara K, Watanabe K.
europepmc   +1 more source

Pharmacokinetic interactions and clinical implications of PPIs and CDKIs in breast cancer: a systematic review and meta-analysis. [PDF]

Syst Rev
Graziosi A, Pane R, Tinazzo E, Basso M, Avantaggiato M, Schianchi A, Canella M, Melis M, Nani A, Del Re M, Danesi R, Pani A, Giossi R, Fornasari D.   +13 more
europepmc   +1 more source

Comparative efficacy of Palbociclib and Everolimus with aromatase inhibitors in second line treatment of HR and HER2 negative metastatic breast cancer. [PDF]

Discov Oncol
Najafizade N, Zarei S, Elhaie M, Roayaei M.   +3 more
europepmc   +1 more source

PIK75 effectively reverses PI3K‒AKT activation caused by palbociclib resistance and synergistically inhibits the progression of esophageal squamous cell carcinoma. [PDF]

Sci Rep
Zhao Y, Li L, Jiang Y, Sun Y, Xu Y, Ye X, Zhang F, Zhu F, Pan Y, Ma S.   +9 more
europepmc   +1 more source

Simultaneous targeting of KRAS and CDK4 synergistically induces durable growth arrest in pancreatic cancer cells. [PDF]

Cell Death Dis
Paulsohn MB, Frahnert KH, Schlösser D, Oschwald J, Kopp W, Fang X, Schneider C, Tapia Contreras C, Danieli-Mackay A, Ludewig F, Bleyer M, Salinas G, Schneider G, Hessmann E, Dobbelstein M.   +14 more
europepmc   +1 more source

Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment. [PDF]

Nat Commun
Boutin J, Fayet S, Marin V, Bergès C, Riandière M, Toutain J, Lamrissi-Garcia I, Thibault C, Cappellen D, Dabernat S, Poulet A, Francillette M, Droin N, Debeissat C, Brunet de la Grange P, Moreau-Gaudry F, Bedel A.   +16 more
europepmc   +1 more source

CDK4/6 inhibitors for premenopausal women with hormone receptor-positive/HER2-negative breast cancer; insight from Young-PEARL. [PDF]

Transl Breast Cancer Res
Tokunaga E.
europepmc   +1 more source