Results 41 to 50 of about 294,621 (346)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Palladium Nanoparticles Synthesized by Pulsed Electrolysis in Room-Temperature Ionic Liquid
International Journal of Electrochemical Science, 2016 Synthesis of palladium nanoparticles by pulsed electrolysis was investigated in the room-temperature ionic liquid 1-butyl-3-methylimidazolium chloride ([C4mim]Cl) using palladium chloride (PdCl2) as the palladium source.
Gwangwon Park +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecules, 2005 We report herein the effect of palladium on the redox electrochemistry of ferrocene monocarboxylic acid encapsulated within an organically modified sol-gel glass network (ORMOSIL).
B. Upadhyay, P. Pandey
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Solubilization of palladium in molten mixture of sodium borates and sodium carbonate
Results in Physics, 2019 Solubility of palladium in water was enhanced by heating metallic palladium in a molten mixture of sodium borates and sodium carbonate at 1000 °C for 2 h.
Takashi Okada +3 more
doaj +1 more source
The Hydrides of Palladium and Palladium Alloys
Platinum Metals Review, 1961 In the second part of this article, concluded from the October issue of ‘Platinum Metals Review’, a short account is given of changes in the physical properties of palladium following absorption of hydrogen. The behaviour of certain palladium alloys is compared with that of palladium and alternative methods of approach towards an understanding of the ...
openaire +1 more source
Recent Advances in Palladium Nanoparticles-Based Hydrogen Sensors for Leak Detection
Italian National Conference on Sensors, 2019 Along with the development of hydrogen as a sustainable energy carrier, it is imperative to develop very rapid and sensitive hydrogen leaks sensors due to the highly explosive and flammable character of this gas.
Cynthia Cibaka Ndaya +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source