Results 81 to 90 of about 505,011 (403)

Prestige for palladium [PDF]

Nature Chemistry, 2010
The 2010 Nobel Prize in Chemistry has been awarded to Richard Heck, Ei-ichi Negishi and Akira Suzuki for palladium-catalysed cross-couplings in organic synthesis.
openaire   +3 more sources

The fluorine-NHC gauche effect: a structural and computational study [PDF]

, 2013
Herein, we report the synthesis and X-ray structural analysis of a collection of fluorinated metal N-heterocyclic carbenes (Ag, Au, Pd, Rh, Ir) and their precursor salts.
Gilmour, R., Paul, S., Rugg, G., Schweizer, W.B., Senn, H.M.   +4 more
core   +1 more source

Biaryl phosphane ligands in palladium-catalyzed amination.

Angewandte Chemie, 2008
Palladium-catalyzed amination reactions of aryl halides have undergone rapid development in the last 12 years, largely driven by the implementation of new classes of ligands.
D. Surry, S. Buchwald
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Palladium-catalyzed allene synthesis enabled by β-hydrogen elimination from sp 2 -carbon

Nature Communications, 2021
β-Hydrogen elimination is a fundamental reaction in palladium catalysis, however, the eliminated β-hydrogen is usually attached to a sp 3 -carbon. Here, the authors report a palladium-catalyzed cross-coupling reaction involving a β-vinylic hydrogen ...
Ge Zhang, Yi-Kang Song, Fang Zhang, Ze-Jian Xue, Meng-Yao Li, Gui-Shan Zhang, Bin-Bin Zhu, Jing Wei, Chunsen Li, Chen-Guo Feng, Guo-Qiang Lin   +10 more
doaj   +1 more source

Tailoring palladium nanocontacts by electromigration [PDF]

, 2013
Electromigration is employed in nanoelectronics for transforming narrow metallic wires into electrodes separated by a few nanometers gap. In this work, we fabricate either nanoconstrictions or nanogap electrodes by performing electromigration in ...
Arzubiaga, Libe, Casanova, Félix, Golmar, Federico, Hueso, Luis E., Llopis, Roger   +4 more
core   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Machine learning to improve HIV screening using routine data in Kenya

Journal of the International AIDS Society
Introduction Optimal use of HIV testing resources accelerates progress towards ending HIV as a global threat. In Kenya, current testing practices yield a 2.8% positivity rate for new diagnoses reported through the national HIV electronic medical record ...
Jonathan D. Friedman, Jonathan M. Mwangi, Kennedy J. Muthoka, Benedette A. Otieno, Jacob O. Odhiambo, Frederick O. Miruka, Lilly M. Nyagah, Pascal M. Mwele, Edmon O. Obat, Gonza O. Omoro, Margaret M. Ndisha, Davies O. Kimanga   +11 more
doaj   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source