Results 211 to 220 of about 1,169,661 (308)

Ultrasound‐Recharged Sub‐Nanometer Palladium Catalysts for on‐Demand and Self‐Terminating Bioorthogonal Prodrug Activation in Cancer Therapy

Advanced Science, EarlyView.
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia, Lei Liu, Shuang Jin, Guangxu Fang, Chang Yu, Yunyun Wu, Lunli Xiang, Hongrui Zhu, Zhenqiang Wang, Jixi Zhang   +9 more
wiley   +1 more source

Syntheses of 2,2'-dihalo-1,1'-binaphthyl compounds via palladium-catalysed 1,2-halo shift-cyclisation coupling reaction of α-hydroxyl haloalkynes. [PDF]

Nat Commun
Ji X, Li Y, Yu WJ, Wu W, Ni SF, Jiang H.
europepmc   +1 more source

PRMT5‐Dependent Stabilization of VPS34 Orchestrates Copper Trafficking to Shield Cancer Cells from Cuproptosis and Radiotherapy

Advanced Science, EarlyView.
Radioresistance arises partly from tumor cells evading cuproptosis via unknown defenses. This study reveals that the PRMT5‐VPS34 axis acts as a radiation‐activated anticuproptotic mechanism: PRMT5 methylates VPS34 at Arg174, recruiting USP10 to remove K48‐linked ubiquitination and prevent degradation.
Wei Chen, Ming‐Ying Xiao, Lan‐Lan Guo, Hao‐Yue Hu, Sui‐Xian Zhang, Bai‐Qiang Dong, Chen‐Fei Wu, Xia‐Hang Huang, Li Li, Run‐Zhe Chen, Yuan‐Yang Huang, Ying Jin, Hai Song, Ying Wang, Qi‐Wen Li, Ming Chen, Xuan Li, Yuan‐Yuan Chen   +17 more
wiley   +1 more source

Continuous-flow synthesis of Pd(ii)-anchored amino-functionalised magnetic silica nanoparticles as a robust recyclable catalyst for aqueous Sonogashira cross-coupling. [PDF]

RSC Adv
Sakee U, Mokkarat A, Radchatawedchakoon W, Kruanetr S, Pilasombat R.   +4 more
europepmc   +1 more source

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

Palladium-catalyzed asymmetric carbofluorination of <i>gem</i>-difluorostyrenes with cesium fluoride and allylic acetates.

Chem Commun (Camb)
Nelson E, Bisoyi RK, Wolf C.
europepmc   +1 more source

In search of the perfect <i>conditions</i> for Suzuki-Miyaura cross-couplings. [PDF]

Front Chem
Lipshutz BH, Oftadeh E, Ortiz M.
europepmc   +1 more source

SrFe₁₂O₁₉ supported Pd complex as a sustainable nanocatalyst for reduction of nitroarenes derivatives. [PDF]

Discov Nano
Abushuhel M, Zaki MEA, Rekha MM, Basheer NM, Ray S, Pal A, Sharma R, Gomha SM, Singh A.   +8 more
europepmc   +1 more source

Development of Mild Palladium-Catalyzed N-Arylation of Ortho-Acylanilines in Rhamnolipid Micellar System. [PDF]

ChemSusChem
Herczegh AR, Kollár PR, Lehmann J, Novák Z.   +3 more
europepmc   +1 more source

Synthesis and multipurpose assessment of Cu(II) and Pd(II) Schiff base complexes as catalysts and antimicrobial agents. [PDF]

Sci Rep
Malav R, Ray S.
europepmc   +1 more source