Results 41 to 50 of about 303,266 (265)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

The pattern of change in opioid and adjuvant prescriptions for cancer pain before and after referral to a comprehensive program in the Palliative Care Center in Kuwait

BMC Palliative Care, 2021
Background Cancer-related pain is a complicated symptom that often coincides with fatigue, depression, and anxiety. Although many safe treatments are available, inadequate control of Cancer-related pain continues to lead to suffering in cancer patients ...
Ameena Mohammed Al-Ansari, Wafaa Mostafa Abd-El-Gawad, Sobhi Mostafa AboSerea, Eman El Sayed ElShereafy, Fatma Abdel Shakor Ali, Mohammed Abd Elaziz ElSayed   +5 more
doaj   +1 more source

Ethnicity, Older People and Palliative Care [PDF]

, 2012
This report brings together established and developing work on older people, ethnicity and palliative care from PRIAE (Policy Research Institute on Ageing and Ethnicity) and the National Council for Palliative Care (NCPC).

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European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

Molecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat, Marc Arbyn, David Baldwin, Xavier Castells, Solveig Hofvind, Urska Ivanus, Carlo Senore, Esther Toes‐Zoutendijk, Carlijn van der Aalst, Carlos Canelo‐Aybar, Fiorella Karina Fernández‐Sáenz, Ariadna Feliu, Hajo Zeeb, Andre L. Carvalho, Erica D'Souza, David Ritchie, Carolina Espina, Iris Lansdorp‐Vogelaar, Andrea DeCensi   +18 more
wiley   +1 more source

Nursing informatics competency and its associated factors among palliative care nurses: an online survey in mainland China

BMC Nursing
Background Nursing informatics (NI) competency is a required core competency for high-quality care in digitally enabled healthcare environments. Given the increasing reliance on digital health in palliative care settings, it becomes crucial to evaluate ...
Junchen Guo, Junqingzhao Liu, Chaoyi Liu, Ying Wang, Xianghua Xu, Yongyi Chen   +5 more
doaj   +1 more source

Midazolam sedation in palliative medicine: retrospective study in a French center for cancer control

BMC Palliative Care, 2020
Background French legislation about sedation in palliative medicine evolved in 2016 with the introduction of a right to deep and continuous sedation, maintained until death.
Vincent Gamblin, Vincent Berry, Emmanuelle Tresch-Bruneel, Michel Reich, Arlette Da Silva, Stéphanie Villet, Nicolas Penel, Chloé Prod’Homme   +7 more
doaj   +1 more source

Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data

BMC Palliative Care, 2022
Background Pain, breathlessness and fatigue are some of the most challenging symptoms to manage in patients with advanced disease. Specialist palliative care leads to better symptom management, but factors contributing to successful symptom management in
Emma J. Chapman, Simon Pini, Zoe Edwards, Yousuf Elmokhallalati, Fliss E. M. Murtagh, Michael I. Bennett   +5 more
doaj   +1 more source

Roles, service knowledge and priorities in the provision of palliative care: a postal survey of London GPs [PDF]

, 2006
Objectives: To explore general practitioners' (GPs) current involvement in and attitudes towards the provision of palliative care in primary care. Methods: Postal survey of 356 London-based GPs, assessing attitudes towards palliative care provision ...
Addington-Hall, J, Burt, J, Shipman, C, White, P   +3 more
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Who Receives Home-Based Perinatal Palliative Care: Experience from Poland [PDF]

, 2013
The current literature suggests that perinatal palliative care (PPC) programs should be comprehensive, initiated early, and integrative. So far there have been very few publications on the subject of home-based PC of newborns and neonates.
Korzeniewska-Eksterowicz, Aleksandra, Kędzierska, Bogna, Młynarski, Wojciech, Przysło, Łukasz, Stolarska, Małgorzata   +4 more
core   +4 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source