Results 41 to 50 of about 185,227 (261)

Midazolam sedation in palliative medicine: retrospective study in a French center for cancer control

BMC Palliative Care, 2020
Background French legislation about sedation in palliative medicine evolved in 2016 with the introduction of a right to deep and continuous sedation, maintained until death.
Vincent Gamblin, Vincent Berry, Emmanuelle Tresch-Bruneel, Michel Reich, Arlette Da Silva, Stéphanie Villet, Nicolas Penel, Chloé Prod’Homme   +7 more
doaj   +1 more source

Adaptation and multicentre validation of a patient-centred outcome scale for people severely ill with COVID (IPOS-COV)

Health and Quality of Life Outcomes, 2023
Background Patient-centred measures to capture symptoms and concerns have rarely been reported in severe COVID. We adapted and tested the measurement properties of the proxy version of the Integrated Palliative care Outcome Scale–IPOS-COV for severe ...
Mevhibe B. Hocaoglu, Fliss E. M. Murtagh, Catherine Walshe, Rachel L. Chambers, Matthew Maddocks, Katherine E. Sleeman, Adejoke O. Oluyase, Lesley Dunleavy, Andy Bradshaw, Sabrina Bajwah, Lorna K. Fraser, Nancy Preston, Irene J. Higginson, the CovPall study team   +13 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Palliative Care

RGUHS Journal of Medical Sciences, 2011
None
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

A National Quality Initiative to Improve Palliative Care Outcomes: Identifying Enabling Factors that Drive Quality Improvement

Palliative Medicine Reports
Background: The Palliative Care Outcomes Collaboration (PCOC), established in 2005 and funded by the Australian Government, is a national quality improvement initiative that integrates patient outcome measures into routine clinical practice.
Sabina Clapham, Katherine Clark, Kylie Draper, Fiorina Mastroianni, Jesse Rand, Lisa Redwood, David Currow   +6 more
doaj   +1 more source

“From good hearted community members we get volunteers” – an exploratory study of palliative care volunteers across Africa

BMC Palliative Care, 2020
Background Volunteers play a significant role in supporting hospice and palliative care in Africa, but little is known about the types of volunteers, their motivations and roles in service delivery.
Carolin Clara Loth, Eve Namisango, Richard Antony Powell, Katharina Henny Pabst, Mhoira Leng, Mohamed Hamada, Lukas Radbruch   +6 more
doaj   +1 more source

Conceptualising effective symptom management in palliative care: a novel model derived from qualitative data

BMC Palliative Care, 2022
Background Pain, breathlessness and fatigue are some of the most challenging symptoms to manage in patients with advanced disease. Specialist palliative care leads to better symptom management, but factors contributing to successful symptom management in
Emma J. Chapman, Simon Pini, Zoe Edwards, Yousuf Elmokhallalati, Fliss E. M. Murtagh, Michael I. Bennett   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Adapting the Serious Illness Conversation communication training workshop from the Western to an Asian context in Singapore

BMC Medical Education
Background/objectives The Serious Illness Care Program (SICP) was developed in the United States and consists of three main componentsthe–Serious Illness Conversation Guide (SICG), Serious Illness Conversation (SIC) communication training, and quality ...
Gillian Li Gek Phua, Radhika Das, Anna So Youn Lee, Annushkha Sharanya Sinnathamby, Prabavathi D/O Balachandran, Swee Noi Tang, Alethea Chung Pheng Yee, Shirlyn Hui-Shan Neo   +7 more
doaj   +1 more source