Results 81 to 90 of about 405,913 (321)

Efficient Computation of Counterfactual Bounds [PDF]

open access: yesarXiv, 2023
We assume to be given structural equations over discrete variables inducing a directed acyclic graph, namely, a structural causal model, together with data about its internal nodes. The question we want to answer is how we can compute bounds for partially identifiable counterfactual queries from such an input.
arxiv  

Palliative Care Is More Care, Not Less [PDF]

open access: yes, 2016
Educational Objectives: 1. Discuss the origins of hospice and palliative care. 2. Compare and contrast Curative, Palliative, and Hospice Models of Care. 3.
Selby-Penczak, Rachel
core   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

“No thanks, I don’t want to see snakes again”: a qualitative study of pain management versus preservation of cognition in palliative care patients

open access: yesBMC Palliative Care, 2020
Background Towards the end of life, use of opioid analgesics becomes more common in patients to control pain and improve quality of life. While pain medication may help manage pain, unwanted cognitive side effects are frequently noted. This balancing act
Pete Wegier   +4 more
doaj   +1 more source

CT Reconstruction from Few Planar X-rays with Application towards Low-resource Radiotherapy [PDF]

open access: yesarXiv, 2023
CT scans are the standard-of-care for many clinical ailments, and are needed for treatments like external beam radiotherapy. Unfortunately, CT scanners are rare in low and mid-resource settings due to their costs. Planar X-ray radiography units, in comparison, are far more prevalent, but can only provide limited 2D observations of the 3D anatomy.
arxiv  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

A Semiparametric Joint Model for Terminal Trend of Quality of Life and Survival in Palliative Care Research [PDF]

open access: yesarXiv, 2016
Palliative medicine is an interdisciplinary specialty focusing on improving quality of life (QOL) for patients with serious illness and their families. Palliative care programs are available or under development at over 80% of large US hospitals (300+ beds).
arxiv  

Bayes Watch: Bayesian Change-point Detection for Process Monitoring with Fault Detection [PDF]

open access: yesarXiv, 2023
When a predictive model is in production, it must be monitored in real-time to ensure that its performance does not suffer due to drift or abrupt changes to data. Ideally, this is done long before learning that the performance of the model itself has dropped by monitoring outcome data.
arxiv  

Health care professionals' perceptions towards lifelong learning in palliative care for general practitioners: a focus group study [PDF]

open access: yes, 2014
Background: There is a growing need for palliative care. The majority of palliative patients prefer their general practitioner (GP) to organize their palliative home care. General practitioners need a range of competences to perform this task.
Deveugele, Myriam   +5 more
core   +2 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy