Results 71 to 80 of about 178,329 (260)

Mapping of Children’s Palliative Care Development Globally in 2023

open access: yesChildren
Background: The demand for children’s palliative care is increasingly urgent, with over 21 million children worldwide needing access, yet only 5–10% currently receiving it.
Julia Downing   +8 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Palliative Care [PDF]

open access: yesSurgical Clinics of North America, 2019
Timothy J, Brown   +2 more
openaire   +4 more sources

Healthcare needs of patients with metastatic cancer and impacts of social vulnerability: a multicentric cross-sectional study in France

open access: yesBMC Palliative Care
Context Understanding the healthcare needs of patients with metastatic cancer is necessary for reducing symptom burden and optimizing supportive care interventions.
Marine Sahut d’Izarn   +12 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

P1743: IDENTIFYING DUTCH HOSPITALIZED PATIENTS AT HEMATOLOGY WARDS WITH A LIMITED LIFE EXPECTANCY: A SUBGROUP ANALYSIS OF A FLASH MOB STUDY

open access: yesHemaSphere, 2022
A. van der Velden   +4 more
doaj   +1 more source

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