Results 111 to 120 of about 289,863 (340)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Some Aspects of Palliative Medicine Teaching to the VI-Year Students of Medicine Faculty

open access: yesGalician Medical Journal, 2016
The study of oncology in medical schools is very important because whatever a doctor will be in the future, at some point he will have to deal with oncologic patients.
A. Ye. Kryzhanivska, I. B. Diakiv
doaj  

From the Warehouse to the Deathbed: Challenging the Conditions of Mass Death in Prison [PDF]

open access: yes, 2015
The purpose of this project is to analyze the crisis of mass incarceration by placing the conditions faced by elderly, terminally ill, and dying prisoners, as its main point of focus.
Chavez, Ernest K
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Palliative care consultations for non-malignant diseases: Experience from a public hospital in Western India

open access: yesJournal of Family Medicine and Primary Care
Background: Palliative care (PC) consultation has been shown to improve patient’s quality of life (QoL), reduce symptom burden, decrease hospital stay, and provide holistic care for patients with life-limiting diseases. Aim: To asses impact of palliative
Shamali Poojary   +5 more
doaj   +1 more source

Emergency Medicine Palliative Care Access (EMPallA): Preliminary Data from a Multi-Center Randomized Controlled Trial [PDF]

open access: yes, 2019
Introduction: Emergency department (ED)-initiated palliative care has been shown to improve patient-centered outcomes in older adults with serious illnesses, but the optimal modality for providing such interventions is unknown. The EMPallA trial compares
Cho, MPH, Jeanne   +4 more
core   +1 more source

Involvement of palliative care in euthanasia practice in a context of legalized euthanasia : a population-based mortality follow-back study [PDF]

open access: yes, 2017
Background: In the international debate about assisted dying, it is commonly stated that euthanasia is incompatible with palliative care. In Belgium, where euthanasia was legalized in 2002, the Federation for Palliative Care Flanders has endorsed the ...
Chambaere, Kenneth   +3 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

Planning for the End of Life for People with Dementia - Part 2 [PDF]

open access: yes, 2011
This publication is a discussion about additional end-of-life options which may become legally available at some time in the future, i.e., assisted death (usually called euthanasia or assisted suicide).
Colleen Cartwright
core   +1 more source

Home - About - Disclaimer - Privacy