Results 41 to 50 of about 111,481 (261)

Bone metastases in breast cancer: Frequency, metastatic pattern and non-systemic locoregional therapy

open access: yesJournal of Bone Oncology, 2014
Background: The study evaluates the frequency of and indications for bone-metastases (BM)-related surgery and/or radiotherapy in the palliative breast cancer (BC) situation and analyzes in which phase of the palliative disease course surgery and/or ...
Kirsten Steinauer   +4 more
doaj   +1 more source

Guidelines for palliative surgery of cholangiocarcinoma [PDF]

open access: yesHPB, 2008
The aims of the guidelines are to help assess the evidence for palliation surgery in patients with cholangiocarcinoma (CCA). The guidelines are classified in accordance with the location of the primary lesion, i.e. intrahepatic, hilar, and distal. They are based on comprehensive literature surveys, including results from randomized controlled trials ...
Witzigmann, H., Lang, H., Lauer, H.
openaire   +2 more sources

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

Natural Language Processing for serious illness communications in palliative surgical oncology

open access: yesAnnals, Academy of Medicine, Singapore
Approximately one-fifth of surgeries performed at major cancer centres worldwide are palliative in nature, and one-third of advanced cancer patients receive surgery during their last year of life.1,2 Serious illness communication (SIC) is an essential ...
Louis Choon Kit Wong   +6 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Usefulness of cell-free and concentrated pleural effusion reinfusion therapy in terminal cancer patients

open access: yesFujita Medical Journal
Objective: Patients with advanced or recurrent cancer often suffer from excessive fluid retention, which substantially affects their quality of life. There are no detailed reports regarding cell-free and concentrated pleural effusion reinfusion therapy ...
Hiroyuki Fujisaki   +7 more
doaj   +1 more source

THE ROLE OF CRYOSURGICAL SURGICAL MEASURES DURING ALVEOLAR LIVER DISEASE REOPERATIONS

open access: yesКреативная хирургия и онкология, 2017
The  results  of  treatment of  36  reoperated patients suffering from   alveolar  liver disease  are analyzed  in the article. The patients were operated according to the know-how offered by one of the work writers.
B. I. Alperovich   +2 more
doaj   +1 more source

Separation Surgery for Unresectable Right-sided Colon Cancer as Palliation

open access: yesJournal of the Anus, Rectum and Colon, 2021
Patients with acute colorectal obstruction due to malignancy in the right-sided colon are treated with primary resection and anastomosis. However, considering the generally poor status and prognosis, less-invasive, palliative treatment is desirable ...
Ryosuke Maki   +5 more
doaj   +1 more source

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

open access: yesAdvanced Functional Materials, EarlyView.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li   +6 more
wiley   +1 more source

Palliative surgery for gastric carcinoma [PDF]

open access: yesGut, 1961
This paper presents practical points concerning palliative surgery for carcinoma of the stomach. The results which may be obtained are evaluated.
openaire   +2 more sources

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