Results 41 to 50 of about 1,639,886 (255)
Cardiovascular Ultrasound, 2017 Background Staged palliative surgery markedly shifts the balance of volume load on a single ventricle and pulmonary vascular bed. Blalock-Taussig shunt necessitates a single ventricle eject blood to both the systemic and pulmonary circulation.
Mao Kinoshita +9 more
doaj +1 more source
Complex Congenital Heart Disease: Echocardiographic Evaluation
Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2020 Various combinations of congenital heart defects are included in complex congenital heart disease. Various pathologies of cardiac structures have varied embryological dysmorphology.
Srinivas Lakshmivenkateshiah +2 more
doaj +1 more source
Palliative care services in Australia 2013 [PDF]
, 2013 This report provides detailed information on the national response to the palliative care needs of Australians. Summary This report on Australian palliative care services is the second in this series.
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Clinical study on anorexia in patients with terminal cancer
Fujita Medical JournalObjectives: Patients with terminal cancer tend to have an increased frequency of a variety of clinical symptoms, including anorexia, at 1 month of life expectancy. This study examined clinical symptoms affecting anorexia in patients with terminal cancer.
Miyo Murai +4 more
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi +9 more
wiley +1 more source
Natural Language Processing for serious illness communications in palliative surgical oncology
Annals, Academy of Medicine, SingaporeApproximately one-fifth of surgeries performed at major cancer centres worldwide are palliative in nature, and one-third of advanced cancer patients receive surgery during their last year of life.1,2 Serious illness communication (SIC) is an essential ...
Louis Choon Kit Wong +6 more
doaj +1 more source
Journal of Bone Oncology, 2014 Background: The study evaluates the frequency of and indications for bone-metastases (BM)-related surgery and/or radiotherapy in the palliative breast cancer (BC) situation and analyzes in which phase of the palliative disease course surgery and/or ...
Kirsten Steinauer +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source