Results 11 to 20 of about 1,842 (159)

Onychoscopy in Palmoplantar Psoriasis: A Comparative Study of Nonpustular Palmoplantar Psoriasis and Palmoplantar Pustulosis [PDF]

Dermatology Practical & Conceptual
Introduction: Palmoplantar psoriasis (PP) is classified as nonpustular psoriasis (NPPP) or palmoplantar pustulosis (PPP). Objective: We sought to shed light on the phenotypic diversity of nail psoriasis (NP) and conducted a thorough study of the ...
Ahu Yorulmaz
doaj   +2 more sources

Could the IL-17 cytokine family be a promising target for the treatment of palmoplantar pustulosis? [PDF]

J Eur Acad Dermatol Venereol
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 728-729, May 2026.
Mrowietz U, Gerdes S.
europepmc   +2 more sources

Apremilast in Japanese patients with palmoplantar pustulosis: A randomized, Phase 3 trial. [PDF]

J Eur Acad Dermatol Venereol
In this Phase 3 trial of Japanese patients with moderate to severe PPP (NCT05174065), significantly more patients achieved PPPASI‐50 at Week 16 with apremilast versus placebo. Patient‐reported outcomes, including pruritus and pain/discomfort, also showed significantly greater decreases at Week 16 with apremilast versus placebo.
Terui T, Okubo Y, Kobayashi S, Morita A, Imafuku S, Tada Y, Abe M, Strober B, Gooderham M, Zhang W, Shimauchi J, Yaguchi M, Kimura T, Ogawa R, Amouzadeh H, Murakami M.   +15 more
europepmc   +2 more sources

Palmoplantar pustulosis and smoking [PDF]

BMJ, 1985
A multicentre case-control study of 216 patients with palmoplantar pustulosis and 626 controls with miscellaneous dermatoses showed a considerably higher prevalence of smoking in the group with palmoplantar pustulosis. This was the first indication that smoking may be an important factor in this skin disease, possibly by affecting the inflammatory ...
Neil H Cox, Simon Ray
  +7 more sources

Palmoplantar pustulosis: pathogenesis, differential diagnosis, and treatment. [PDF]

J Dtsch Dermatol Ges
Summary Palmoplantar pustulosis (PPP) is a chronic inflammatory and often painful disease characterized by sterile pustules on the palms and soles, significantly impairing quality of life. Women are more frequently affected than men, and smoking is a major trigger. Under biologic therapies, especially TNF antagonists, a paradoxical PPP may occur.
Mössner R, Fetter T, Sabat R, Mrowietz U, Cramer N, Wilsmann-Theis D.   +5 more
europepmc   +2 more sources

Lack of association between mutation in IL36RN and palmoplantar pustular psoriasis in Chinese patients, [PDF]

Anais Brasileiros de Dermatologia, 2020
Background: Palmoplantar pustulosis is considered to be a localized pustular psoriasis confined to the palms and soles. Mutation of the IL36RN gene, encoding interleukin-36 receptor antagonist (IL-36Ra), is associated with generalized pustular psoriasis,
Yu Xiaoling, Shu Dan, Jin Hongzhong
doaj   +1 more source

Clinical characteristics and associations of palmoplantar pustulosis: an observational study, [PDF]

Anais Brasileiros de Dermatologia, 2020
Background: Palmoplantar pustulosis is a chronic and relapsing disease of the palms and soles, which is characterized by scattered clusters of pinhead-sized, sterile pustules. Objective: The aim of the present study was to determine demographic features,
Ayse Oktem, Pınar Incel Uysal, Neslihan Akdoğan, Aslı Tokmak, Basak Yalcin   +4 more
doaj   +1 more source

Economic Burden of Palmoplantar Pustulosis in Sweden: A Population-based Register Study

Acta Dermato-Venereologica, 2023
The aim of this study was to estimate the economic burden of palmoplantar pustulosis, a chronic relapsing skin condition commonly occurring in combination with psoriasis vulgaris.
Sofia Löfvendahl, Jenny M. Norlin, Marcus Schmitt-Egenolf   +2 more
doaj   +1 more source

IL-36 Receptor Antagonist Spesolimab for Generalized Pustular Psoriasis Combined with Palmoplantar Pustulosis: A Case Report [PDF]

Clinical, Cosmetic and Investigational Dermatology
Hongyan Tan,1,* Yu Zhang,2,* Bin Zhang,3 Juan Wang,3 Zhong Zhang,3 Jizhen Zhong,3 Xiao Qiu,3 Xiangyu Hu,3 Ling Tang4 1Department of Dermatology, Shantou Hospital of Traditional Chinese Medicine, Shantou, 515031, People’s Republic of China;
Tan H, Zhang Y, Zhang B, Wang J, Zhang Z, Zhong J, Qiu X, Hu X, Tang L   +8 more
doaj   +1 more source

Efficacy and safety of brodalumab in palmoplantar pustulosis: A 68-week randomized Phase 3 trial. [PDF]

J Eur Acad Dermatol Venereol
This open‐label study is a continuation of the 16‐week double‐blind, Phase 3 trial assessing the efficacy and safety of brodalumab 210 mg subcutaneously, till a 68‐week extension period. Continued improvement was seen in the PPPASI 50/75/90 responses, PPPSI scores, PGA 0/1 responses and DLQI. Abstract Background The efficacy and safety of brodalumab in
Murakami M, Okubo Y, Kobayashi S, Kikuta N, Ouchi Y, Shishido K, Terui T.   +6 more
europepmc   +2 more sources