JAK inhibitors for the treatment of palmoplantar pustulosis: a narrative review [PDF]
Background: Palmoplantar pustulosis (PPP) is a chronic, relapsing skin condition characterized by sterile, pruritic pustules on erythematous, thickened skin of the palms and soles.
Beatriz Henriques dos Santos +3 more
doaj +3 more sources
Economic Burden of Palmoplantar Pustulosis in Sweden: A Population-based Register Study
The aim of this study was to estimate the economic burden of palmoplantar pustulosis, a chronic relapsing skin condition commonly occurring in combination with psoriasis vulgaris.
Sofia Löfvendahl +2 more
doaj +2 more sources
Palmoplantar Pustulosis: A Case Report [PDF]
Introduction: Dermatology complaints account for 3.3% of emergency department (ED) visits per year. Most rashes are benign, but there are a select few that emergency physicians must be familiar with as delay in treatment could be life threatening.
Anne Dulski, Vince Varamo
doaj +2 more sources
Research progress on phosphodiesterase 4 inhibitors in the treatment of palmoplantar pustulosis
Palmoplantar pustulosis (PPP) is a chronic recurrent inflammatory skin disease. Existing therapeutic methods cannot meet the demand by patients. Phosphodiesterase-4 (PDE-4) is a key enzyme involved in the balance of immunocytes.
YAO Xinyi +3 more
doaj +2 more sources
In recent years, with the increased usage of tumour necrosis factor (TNF) inhibitors, more side effects have been revealed. Paradoxical psoriasis, including psoriasis vulgaris, palmoplantar pustulosis, scalp psoriasis and their combinations, is a common ...
Ying Wang, Yong Cui, Zhancai Zheng
doaj +2 more sources
Topical Crisaborole for the Treatment of Recalcitrant Palmoplantar Pustulosis: A Case Series [PDF]
Palmoplantar pustulosis (PPP) is a chronic, relapsing disease with sterile pustules involving the palms and soles. The pathogenesis of PPP remains unclear and there is currently no standard treatment.
Yen-Yi Sung, Tsen-Fang Tsai
doaj +2 more sources
Janus kinase inhibitors in palmoplantar pustulosis: a mixed-methods feasibility (JAKPPPOT) trial protocol [PDF]
Background Palmoplantar pustulosis (PPP) is a rare, debilitating inflammatory skin disease involving painful pustules on the palms and soles. Janus kinase (JAK) inhibitors target pathways relevant to PPP disease biology but also confer a risk of major ...
Weiyu Ye +17 more
doaj +2 more sources
Palmoplantar pustulosis : an autoimmune disease precipitated by smoking
Ninety-five percent of patients with palmoplantar pustulosis are smokers at onset of the disease. The aim of this study was to determine whether these patients have serum antibodies to nicotinic acetylcholine receptors (nAChR ab) and if their sera induce
Lefvert, Ann-Kari +4 more
core +9 more sources
IL-36 Receptor Antagonist Spesolimab for Generalized Pustular Psoriasis Combined with Palmoplantar Pustulosis: A Case Report [PDF]
Hongyan Tan,1,* Yu Zhang,2,* Bin Zhang,3 Juan Wang,3 Zhong Zhang,3 Jizhen Zhong,3 Xiao Qiu,3 Xiangyu Hu,3 Ling Tang4 1Department of Dermatology, Shantou Hospital of Traditional Chinese Medicine, Shantou, 515031, People’s Republic of China;
Tan H +8 more
doaj +2 more sources
Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis [PDF]
The PSORS1 locus in the major histocompatibility complex region is the major genetic determinant for psoriasis vulgaris. Within the PSORS1 region reside at least three potential candidate genes for psoriasis susceptibility.
Burden, David A. +17 more
core +11 more sources

