Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Towards Identifying PAMPs from the Downy Mildew Pathogen Hyaloperonospora Arabidopsidis
Downy mildews are oomycete microbes and obligate parasites, belonging to the Order Peronosporales. They display a variety of hosts, infecting crop plants belonging to different families, such as lettuce, grapevine or tomato, but also ornamental plants ...
Fantozzi, Elena +3 more
core
Molecular Structure Regulation of Polyacrylamide-Based Drag Reducers on Solubility and Transient Gel-Layer Behavior: Molecular Dynamics and Experimental Study. [PDF]
Xu K +8 more
europepmc +1 more source
Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Gut-derived bacterial extracellular vesicles: the microbial dark matter contributing to host inflammation and cardiometabolic disease. [PDF]
Oliver B +6 more
europepmc +1 more source
LURP1, a SARD1‐regulated protein, coordinates with the helper NLR ADR1 to promote plant immunity
The working model of LURP1 function in plant immunity. Upon pathogen infection, SARD1/CBP60g promotes the transcription of LURP1 directly. LURP1 likely functions as an adaptor protein that associates with the PRRs–BAK1 complexes at the plasma membrane (PM) while also interacts with the ADR1 family helper NLRs.
Xueru Liu +7 more
wiley +1 more source
Leveraging the bacteria for enhanced cancer immunotherapy: from a perspective of synthetic biology. [PDF]
Liu X +5 more
europepmc +1 more source
Jasmonate signalling underpins establishment of plant systemic acquired resistance (SAR). Activation of the hypersensitive response (HR) not only contains the pathogen but establishes broad spectrum resistance in unchallenged leaves. The strong burst of reactive oxygen/nitrogen species initiating the HR results in lipid peroxidation (illustrated by ...
Fay Bennett +3 more
wiley +1 more source
Hintergrund: Durch direkten Kontakt, Nahrungsaufnahme und Inhalation ist das humane Immunsystem praktisch andauernd einer Vielzahl an potentiellen Pathogenen ausgesetzt.
Felsberger, Martin
core
Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
wiley +1 more source

