Alimentary Pharmacology &Therapeutics, Volume 64, Issue 7, Page 897-918, October 2026.Individualized assessment identifies patients with decompensated autoimmune hepatitis cirrhosis who are likely to benefit from a time‐limited trial of immunosuppression versus those requiring immediate liver transplant evaluation. Early objective response monitoring (bilirubin, MELD‐Na and AST/ALT) guides continuation of immunosuppression, promotes ...
Pedro Robson Costa Passos +2 more
wiley +1 more source
Acute-on-chronic liver failure and immune dysregulation: Systemic inflammation and immunoparesis paradox. [PDF]
Hepatol CommunDrago AA +8 more
europepmc +1 more source
The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.Increasing evidence indicates an association between type 2 diabetes mellitus and Alzheimer’s disease, contributing to the proposed concept of AD as “type 3 diabetes.” Shared biological features such as impaired insulin signaling, chronic inflammation, mitochondrial dysfunction, and oxidative stress have been observed in both T2DM and AD.
Deniz Catakli +3 more
wiley +1 more source
Beyond pathogens: a narrative review of the immunological nexus of damage-associated molecular patterns and inflammasome activation in sterile AECOPD. [PDF]
Front ImmunolPeng C +7 more
europepmc +1 more source
Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola
Insect Molecular Biology, Volume 35, Issue 5, Page 576-593, October 2026.Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez +1 more
wiley +1 more source
The gut-joint axis in gout: microbial outer membrane vesicles and m<sup>6</sup>A-mediated metabolic-epigenetic coupling from acute flare to chronicity. [PDF]
Front ImmunolQi Y, Bai J, Liu D, Wang S.
europepmc +1 more source
Journal of Fish Diseases, Volume 49, Issue 10, October 2026.ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English +4 more
wiley +1 more source
Regulation of Innate Immune Signaling by Autophagy. [PDF]
Int J Mol SciOña-Sánchez D +2 more
europepmc +1 more source
Insights Into the Role of Lysine Acetylation of Non‐Histone Proteins in Plant Immunity
Plant, Cell &Environment, Volume 49, Issue 10, Page 7604-7618, October 2026.ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Jérémy Villette +5 more
wiley +1 more source
Immunological mechanisms and precision stratification in male infertility: from testicular immune privilege and danger signal amplification to seminal immune biomarkers and mechanism-tailored intervention. [PDF]
Front ImmunolZhou J +5 more
europepmc +1 more source