Integrating nanomedicine and immunotherapy: Bacterial membrane-derived vesicle-encapsulated prodrug assemblies for chronic infections. [PDF]
Zhong X +6 more
europepmc +1 more source
Background: Contagious ecthyma (Orf) is a highly contagious, economically significant disease affecting sheep, goats and wild small ruminants, caused by the resilient Orf virus (ORFV). It produces thick, crusted lesions around the mouth and nostrils, especially in animals aged 3–4 months, sometimes causing near 100% mortality in immunocompromised young
Emine Nur Dincer, Ozlem Ozmen
wiley +1 more source
Pyroptosis, A Double-Edged Sword in Respiratory Diseases: A Narrative Review. [PDF]
Yu C, Dai C, Zhu L.
europepmc +1 more source
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury
Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley +1 more source
Gas plasma-induced bacterial PAMP release promotes skin cancer cell death. [PDF]
Berner J +5 more
europepmc +1 more source
The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation
ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao +4 more
wiley +1 more source
Profiling of human and microbial cell-free DNA reflects early host-pathogen interactions in sepsis. [PDF]
Hoeter K +8 more
europepmc +1 more source
Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal +2 more
wiley +1 more source
The bug, the burden, and the biology: beyond host-centric phenotyping in sepsis. [PDF]
Kitsios GD, Baron RM.
europepmc +1 more source
A schematic representation illustrating the preparation of BGNP@YM and its therapeutic effects on septic mice induced by lipopolysaccharide (LPS). (A) BBR is first encapsulated within GNPs to form BGNPs with anti‐inflammatory activity, which are subsequently coated with YM via chemical precipitation to obtain the BGNP@YM oral delivery system.
Qing‐Qing Dong +6 more
wiley +1 more source

