Results 31 to 40 of about 113,393 (217)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Polyarteritis Nodosa Presenting with Ischemic Stroke: A Case Report [PDF]
Disease and DiagnosisPolyarteritis nodosa (PAN) is a rare inflammatory necrotizing vasculitis with variable clinical manifestations and unusual presentations. Therefore, delays in diagnosis are common.
Samaher Almousa +5 more
doaj +1 more source
Pan, Syrinx and syringomyelia [PDF]
Arquivos de Neuro-Psiquiatria, 2017 ABSTRACT Many myths and legends have had a deep influence on modern language, and on modern medical vernacular. The terms “syrinx” and “panic”are two of the most characteristic examples and their use in neurology and other specialties is well known. This article reviews the history of these words in Greek mythology and their use in modern medicine.
Palacios-Sánchez, Leonardo +2 more
openaire +6 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Gladius, 2014 El rey fue la figura más importante de todo el período helenístico. Fue un guerrero invencible, un gobernante sabio, dios, general y curador. Todos estos aspectos sobre la monarquía helenística son bien conocidos, sin embargo hay una cuestión que no ha ...
Antonio Ignacio Molina Marín
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Bread provision in seventeenth century Madrid
Studia Historica: Historia Moderna, 2012 Bread market was the most important provision markets, so the complexity of intervention system. The aim of provision policy was to guarantee the continuous supply of bread at moderate and stable prices.
José Ignacio ANDRÉS UCENDO +1 more
doaj
One health ethics: “What then must we do?”*
CABI One Health, 2022 One Health, as proclaimed by the United Nations Quadripartite, is “an integrated, unifying approach that aims to sustainably balance and optimize the health of people, animals, and ecosystems.” As such, it recognizes that the health of people, other ...
Joann M. Lindenmayer +7 more
doaj +1 more source