Results 41 to 50 of about 18,267 (186)

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

VIEW, EarlyView.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu, Linlin Cao, Chenhuan Ding, Chen Wang, Yi Lai, Dan Ru, He Li, Wei Xu   +7 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

The complete plastome of Panax stipuleanatus: Comparative and phylogenetic analyses of the genus Panax (Araliaceae)

Plant Diversity, 2018
Panax stipuleanatus (Araliaceae) is an endangered and medicinally important plant endemic to China. However, phylogenetic relationships within the genus Panax have remained unclear. In this study, we sequenced the complete plastome of P.
Changkun Liu, Zhenyan Yang, Lifang Yang, Junbo Yang, Yunheng Ji   +4 more
doaj   +1 more source

Identification and differentiation of Panax ginseng, Panax quinquefolium, and Panax notoginseng by monitoring multiple diagnostic chemical markers

Acta Pharmaceutica Sinica B, 2016
To differentiate traditional Chinese medicines (TCM) derived from congeneric species in TCM compound preparations is usually challenging. The roots of Panax ginseng (PG), Panax quinquefolium (PQ) and Panax notoginseng (PN) are used as popular TCM. They contain similar triterpenoid saponins (ginsenosides) as the major bioactive constituents.
Wenzhi Yang, Xue Qiao, Kai Li, Jingran Fan, Tao Bo, De-an Guo, Min Ye   +6 more
openaire   +3 more sources

The BAHD Acyltransferase Gene Family: Evolutionary Dynamics, Biochemical Mechanisms, and Roles in Plant Stress Adaptation

Plant Biotechnology Journal, EarlyView.
BAHD acyltransferases drive metabolic diversification in plants by coupling conserved catalytic scaffolds with regulatory flexibility, enabling stress adaptation and ecological specialisation. ABSTRACT BAHD acyltransferases constitute one of the most versatile enzyme superfamilies in plants, catalysing the acylation of alcohols, amines, polyamines, and
Muhammad Mubashar Zafar, Qiao Fei, Abdul Razzaq, Ayesha Siddiqua, Ayesha Naveed, M. Nasir Khan, Huma Saleem, Xuefei Jiang   +7 more
wiley   +1 more source

Development of a single-tube nested PCR-lateral flow biosensor assay for rapid and accurate detection of Alternaria panax Whetz. [PDF]

PLoS ONE, 2018
Alternaria panax Whetz causes one of the most commonly occurring and serious diseases in ginseng cultivation, and may cause significant production and economic losses in the ginseng industry.
Shuqin Wei, Yajuan Sun, Guangsheng Xi, Huijuan Zhang, Mingya Xiao, Rui Yin   +5 more
doaj   +1 more source

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, EarlyView.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao, Yuan Zong, Tao Wang, Jianan Li, Zengrong Ye, Famei Zhang, Guoying Zhou   +6 more
wiley   +1 more source

Mechanism study on improving chloropicrin fumigation effect by covering fumigated soil with appropriate thickness film

Frontiers in Microbiology
IntroductionPanax notoginseng, a perennial medicinal plant, suffers from severe continuous cropping obstacles. Chloropicrin (CP) as a soil fumigant can be used to effectively mitigate continuous cropping obstacles.
Chunyan Dai, Chunyan Dai, Minghua Li, Minghua Li, Rongfeng Pu, Rongfeng Pu, Yameng Lin, Yameng Lin, Hualin Liu, Hualin Liu, Yuan Liu, Yuan Liu, Xiuming Cui, Xiuming Cui, Peiran Liao, Ye Yang, Ye Yang   +16 more
doaj   +1 more source

ОПТИМИЗАЦИЯ ЭКСТРАГИРОВАНИЯ АКТИВНЫХ ВЕЩЕСТВ КАЛЛУСНЫХ И КОРНЕВЫХ КУЛЬТУР PANAX GINSENG

Ползуновский вестник, 2021
Panax ginseng является самым ценным и известным тонизирующим препаратом в традиционной китайской медицине. В нем сосредоточено значительное количество биологически активных веществ, которые имеют антиоксидантные, антимикробные, противоопухолевые и ...
Анастасия Михайловна Федорова, Анна Ивановна Лосева, Любовь Сергеевна Дышлюк, Варвара Ивановна Минина   +3 more
doaj