Results 61 to 70 of about 2,527 (142)

Immunoprotective potential of steamed Panax notoginseng saponins: chemical characterization and mechanistic insights via the TLRs/NF-κB pathway

open access: yesJournal of Agriculture and Food Research
Steamed Panax notoginseng (SPN) has long been consumed as a functional food for immune support, yet its active constituents and mechanisms remain incompletely defined.
Min Gao   +7 more
doaj   +1 more source

TCM‐Guided Targeted Therapies Against NLRP3 Inflammasome in NAFLD

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
This graphical abstract illustrates TCM syndrome differentiation‐guided targeted strategies against NLRP3 inflammasome‐mediated non‐alcoholic fatty liver disease (NAFLD). Metabolic dysfunction and gut‐liver axis dysregulation drive NAFLD progression, activating the NLRP3 inflammasome (comprising NLRP3, ASC, caspase‐1) to trigger cytokine release (IL‐1β,
Yanxia Zhang
wiley   +1 more source

Genetic Identification ofPanax ginsengandPanax quinquefoliusby Pyrosequencing Methods

open access: yesBioscience, Biotechnology, and Biochemistry, 2005
This study was performed to determine whether two ginseng species (Panax ginseng and Panax quinquefolius) can be identified by genetic analysis and to verify pyrosequencing analysis, which was used to assess genetic variation. The pyrosequencing results constituted clear data.
LEEM, Kanghyun   +3 more
openaire   +2 more sources

Agrobacterium-mediated Transformation of Mature Ginseng Embryos

open access: yesBio-Protocol, 2014
Ginseng refers to species within the genus Panax and is a slow-growing perennial herb from the Araliaceae family. The most widely used Panax species is Panax ginseng Meyer (Korean ginseng).
Ok Ran Lee, Jin Han, Yoon-Ri Kim
doaj   +1 more source

Vacuolization as a Novel Approach to Cancer Therapy

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak   +9 more
wiley   +1 more source

Efficacy and Safety of Ginseng Berry Extract (SIRTBERRYTM) in Treating Andropause Symptoms: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

open access: yesThe World Journal of Men's Health
Purpose: This study aimed to evaluate the efficacy and safety of ginseng berry extract (GBE) (SIRTBERRYTM) in treating andropause symptoms in aging men.
Sun-Young Park   +5 more
doaj   +1 more source

Exogenous salicylic acid treatment enhances the disease resistance of Panax vietnamensis by regulating secondary metabolite production

open access: yesFrontiers in Plant Science
IntroductionSalicylic acid (SA) is a phenolic compound widely found in plants. It plays a key role in exerting plant disease resistance. Panax vietnamensis Ha & Grushv., a valuable medicinal plant, contains high levels of phenolic compounds, which ...
Jiae Hou   +20 more
doaj   +1 more source

Unveiling Active Constituents and Potential Targets Related to the Hematinic Effect of Steamed Panax notoginseng Using Network Pharmacology Coupled With Multivariate Data Analyses

open access: yesFrontiers in Pharmacology, 2019
Steamed Panax notoginseng (SPN) has been used as a tonic to improve the blood deficiency syndrome (BDS) in the theory of traditional Chinese medicine. Here, we aim to unveil active constituents and potential targets related to the hematinic effect of SPN,
Yin Xiong   +10 more
doaj   +1 more source

Encephalopathy: Cause, Pathogenesis, and Treatment

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv   +7 more
wiley   +1 more source

Microbes as carbendazim degraders: opportunity and challenge

open access: yesFrontiers in Microbiology
Carbendazim (methyl benzimidazol-2-ylcarbamate, CBZ) is a systemic benzimidazole carbamate fungicide and can be used to control a wide range of fungal diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes.
Yi Zhou   +9 more
doaj   +1 more source

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