Results 61 to 70 of about 5,828 (173)

17‐β‐Estradiol Protects Chondrocytes From Senescence and Ameliorates Osteoarthritis Progression via ERα‐AKT‐FOXO4 Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Osteoarthritis (OA) is a prevalent cause of joint pain in elderly individuals, and chondrocyte senescence plays a crucial role in its pathogenesis. FOXO4 has been identified as a crucial molecule in cellular senescence. However, little is known regarding its role in OA and the regulation of its expression.
Yikai Liu, Jiangshan Ai, Zian Zhang, Xinzhe Lu, Chaoqun Yu, Yejun Zha, Haining Zhang   +6 more
wiley   +1 more source

Microbes as carbendazim degraders: opportunity and challenge

Frontiers in Microbiology
Carbendazim (methyl benzimidazol-2-ylcarbamate, CBZ) is a systemic benzimidazole carbamate fungicide and can be used to control a wide range of fungal diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes.
Yi Zhou, Tianyue Wang, Liping Wang, Pengfei Wang, Feiyu Chen, Pankaj Bhatt, Shaohua Chen, Xiuming Cui, Ye Yang, Wenping Zhang   +9 more
doaj   +1 more source

Panax notoginseng saponins improve recovery after spinal cord transection by upregulating neurotrophic factors

Neural Regeneration Research, 2015
Saponins extracted from Panax notoginseng are neuroprotective, but the mechanisms underlying this effect remain unclear. In the present study, we established a rat model of thoracic (T 10 ) spinal cord transection, and injected Panax notoginseng saponins
Bo Wang, Yu Li, Xuan-peng Li, Yang Li
doaj   +1 more source

Stereoisomers of Saponins in Panax notoginseng (Sanqi): A Review [PDF]

Frontiers in Pharmacology, 2018
Panax notoginseng (Sanqi), a traditional Chinese medical drug which has been applied to medical use for over four centuries, contains high content of dammarane-type tetracyclic triterpenoid saponins. A number of stereoisomeric dammarane-type saponins exist in this precious herb, and some are particularly regarded as "biomarkers" in processed ...
Ming Peng, Ming Peng, Ya X. Yi, Tong Zhang, Yue Ding, Jian Le, Jian Le   +6 more
openaire   +3 more sources

Prevention of In‐Stent Restenosis After PCI by Saponin Natural Products: Inhibition of Platelet Activation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Percutaneous coronary intervention (PCI) enables coronary revascularisation and restores haemodynamic stability but also carries risks of delayed complications including in‐stent restenosis (ISR), a chronic progressive disease with endovascular damage after PCI, which compromises the long‐term efficacy of PCI.
Xueli Lei, Chunlei Lv, Yu Zhang, Zhiyu Li, Hao Shen, Li Zhu   +5 more
wiley   +1 more source

The effects of different hormone combinations on the growth of Panax notoginseng anther callus based on metabolome analysis

Frontiers in Plant Science
Panax notoginseng saponins (PNS), the primary active components of Panax notoginseng (Burk.) F.H.Chen, a traditional and precious Chinese medicinal herb, are mainly derived from the roots of the plant.
Saiying Yu, Saiying Yu, Leilin Li, Leilin Li, Tiantai Liu, Tiantai Liu, Jianbin Li, Jianbin Li, Qian Yang, Qian Yang, Qian Yang, Qian Yang, Qian Yang, Xiuming Cui, Xiuming Cui, Xiuming Cui, Xiuming Cui, Xiuming Cui   +17 more
doaj   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, Volume 600, Issue 2, Page 164-187, January 2026.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

Coupling effects of irrigation level and terrain slope on disease, yield and quality of Panax notoginseng under micro-sprinkler irrigation

Agricultural Water Management
At present, the state has introduced the policy of forest Chinese herbal medicine planting planning, strictly prohibiting the planting of Chinese herbal medicine in basic farmland, coupled with the fact that the continuous cropping obstacles of Panax ...
Jiankai Tang, Xiulu Yue, Qiliang Yang, Jiaping Liang, Haidong Wang   +4 more
doaj   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

Animal Models and Experimental Medicine, Volume 9, Issue 1, Page 50-58, January 2026.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang, Siman Sun, Xiaoyu Fan, Jiuming He, Qing Li, Hongtao Jin   +5 more
wiley   +1 more source

Multi-layered effects of Panax notoginseng on immune system

Pharmacological Research
Recent research has demonstrated the immunomodulatory potential of Panax notoginseng in the treatment of chronic inflammatory diseases and cerebral hemorrhage, suggesting its significance in clinical practice. Nevertheless, the complex immune activity of
Chunhao Yang, Liping Qu, Rui Wang, Feifei Wang, Zhaoxiang Yang, Fengkun Xiao   +5 more
doaj   +1 more source