Results 221 to 230 of about 73,601 (288)

Delivery of nano‐formulated drugs to solid tumours is selectively increased by co‐application of the vascular disrupting agent CA4P

British Journal of Pharmacology, EarlyView.
Background and purpose Nano‐formulated chemotherapeutics prolong systemic availability of drugs and can reduce systemic toxicity, but their accumulation in solid tumours is often limited and unpredictable. Broadly applicable strategies to selectively enhance tumour delivery are lacking.
Annabel Kitowski, Constanze Heise, Stefanie Sperling, Jasmin Hotz, Danica Bajic, Marina Rubey, Kathrin Klar, Georg Höfner, Julien Vollaire, Veronique Josserand, Jean‐Luc Coll, Oliver Thorn‐Seshold, Petar Marinković, Julia Thorn‐Seshold   +13 more
wiley   +1 more source

Stereotactic Adaptive Radiation Therapy for Borderline Resectable or Locally Advanced Pancreatic Cancer to Minimize Gastrointestinal Toxicity (ARTIA-Pancreas): Protocol for a Single-Arm Prospective Trial.

JMIR Res Protoc
Henke LE, Kim H, Laugeman E, Kohlmyer S, McCann C, Pietrovito K, Russell K, Woo J, Price AT.   +8 more
europepmc   +1 more source

PID-controller enhanced artificial β-cells. [PDF]

PLoS One
Liu L, Jacobson B, Stefanovic D.
europepmc   +1 more source

Docetaxel‐Induced Immune Activation Shows Antitumor Synergy With the Tumor‐Targeted CD40 Agonist KK2269

Cancer Science, EarlyView.
CD40 agonists have demonstrated proof‐of‐concept for converting an immunologically cold tumor into a hot tumor in preclinical studies; however, clinically, they have shown limited antitumor efficacy as monotherapy. We tested a tumor‐targeted CD40 agonist, KK2269 (a bispecific antibody that binds to CD40 and EpCAM), in combination with various ...
Yuta Tezuka, Kyoko Kawasaki, Yoshiki Sumitomo, Masato Saito, Akari Yao, Munetoshi Ando   +5 more
wiley   +1 more source

Editorial: Innovative AI approaches in quantitative MRI: from image enhancement to biomarker estimation. [PDF]

Front Radiol
Mastropietro A, Scalco E, Figini M.
europepmc   +1 more source

Cadaveric addendum to the consensus on ultrasound‐based lymph‐node staging in gynecological cancer

Ultrasound in Obstetrics &Gynecology, EarlyView.
D. Fischerova, E. Farsi, E. Facchetti, E. Panizzolo, G. Gambino, H. Reina, F. Sousa, M. R. Kadajari, N. Tiszlavicz, G. Garganese, O. Nanka, Collaborators, E. Gatti, C. Culcasi   +13 more
wiley   +1 more source

Lactate‐Induced Liquid–Liquid Phase Separation of HIF‐1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer

Cell Proliferation, EarlyView.
Lactate‐Induced Liquid‐Liquid Phase Separation of HIF‐1α Drives Myeloid Cell Polarization and Immune Evasion in Colorectal Cancer.
Chenhao Fu, Xiang Chen, Haoyu Huang, Lipeng Zhang, Haonan Huang, Fan Jiang, Fayang Lei, Honglong Yu, Jibiao Liu, Houping Zhang, Kan Dai, Zhixiong Wu, Huizi Li, Xi‐jian Dai, Shengxun Mao   +14 more
wiley   +1 more source

Artificial intelligence-based models for quantification of intra-pancreatic fat deposition and their clinical relevance: a systematic review of imaging studies. [PDF]

Eur Radiol
Joshi T, Virostko J, Petrov MS.
europepmc   +1 more source

Banting memorial lecture 2025: Aligning clinical practice, policy and research

Diabetic Medicine, EarlyView.
Abstract National clinical leadership, on a background of clinical practice and clinical research, provides unique perspectives. I have focused the Banting Memorial Lecture 2025 on the implementation of national programmes across England since 2013, for which, along with colleagues at NHS England, I successfully made the case for investment, led the ...
Jonathan Valabhji
wiley   +1 more source