Results 231 to 240 of about 39,435 (300)

The Fatty Pancreas: Current Evidence, Treatment Implications, and Future Directions. [PDF]

open access: yesGastro Hep Adv
Syed KA   +6 more
europepmc   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Trustworthy artificial intelligence in predictive medicine: cancer survival analysis using ethical-by-design and explainable artificial intelligence models. [PDF]

open access: yesJAMIA Open
Farahani S   +12 more
europepmc   +1 more source

ALDH2 Polymorphism in Alcohol‐Related Cirrhosis Requiring Liver Transplantation: A Recipient–Donor Analysis

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim Genetic polymorphisms of alcohol‐metabolizing enzymes influence drinking behavior and susceptibility to alcohol‐related liver disease (ALD). This study aimed to clarify the distribution of ALDH2 and ADH1B genotypes in liver transplant recipients with ALD, and to explore associations with post‐transplant drinking behavior using a recipient ...
Noriyo Yamashiki   +3 more
wiley   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota   +3 more
wiley   +1 more source

Circadian Deregulation in Multiple Myeloma: BMAL1/CLOCK Expression Patterns and Diagnostic Performance

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak   +6 more
wiley   +1 more source

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