Results 251 to 260 of about 488,511 (298)

Closed‐Loop Bioelectronic Artificial Pancreas Patch for Continuous Monitoring and Regulation of Blood Glucose in Diabetic Rats and Pigs

Advanced Science, EarlyView.
A closed‐loop bioelectronic artificial pancreas patch is presented for glucose monitoring and regulation. Utilizing transiently dissolvable microneedle arrays integrated with microtube arrays, the patch efficiently delivers insulin into interstitial fluid, eliminating the need for external long needles. In diabetic pigs, it demonstrates excellent blood
Yiqun Liu, Changxi Zhang, Lingyi Xu, Yuan Ma, Yuanyuan Ma, Ying Chen, Difei Lu, Le Ye, Li Yang, Yue Cui   +9 more
wiley   +1 more source

Early Celiac Plexus Block in Metastatic Pancreatic Cancer: A Case Report. [PDF]

Clin Case Rep
Fardman B, Sheedy C, Raymond J.
europepmc   +1 more source

Hepatic ENTPD5 Is Critical for Maintaining Metabolic Homeostasis and Promoting Brown Adipose Tissue Thermogenesis

Advanced Science, EarlyView.
ENTPD5‐mediated conversion of extracellular adenosine triphosphate to ADP of hepatocytes is critical for maintaining hepatic glucose/lipid metabolism and promoting brown adipose tissue thermogenesis via the inhibition of adrenomedullin expression and secretion.
Rufeng Ma, Song Hou, Rui Xiang, Wenjun Liu, Xin Li, Yujing Chi, Ming Xu, Haochen Yao, Jing Li, Jichun Yang   +9 more
wiley   +1 more source

One-Year HbA1c Predicts Long-Term Pancreas Graft Survival Following SPK Transplantation: A US Population Cohort Study. [PDF]

Transpl Int
Kourounis G, Tingle SJ, Maillo-Nieto A, Wroe C, Thompson ER, Owen R, van Leeuwen L, Holzner M, Wadhera V, Zeeshan Akhtar M, Florman S, Shaw J, White S, Wilson C.   +13 more
europepmc   +1 more source

Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK‐3β/β‐Catenin Signaling

Advanced Science, EarlyView.
FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan, Dan Guo, Songtao Li, Jinmiao Tian, Chaotong Zhang, Zhuoyu Li   +5 more
wiley   +1 more source

SMARCA4-Deficient Undifferentiated Carcinoma: A Report of 2 Cases. [PDF]

Am J Case Rep
Kim SH, Park K, Kim JC, Kim J, Park DJ, Lee HJ, Yang HK, Kwak Y, Kong SH.   +8 more
europepmc   +1 more source

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

MDMU-Net: 3D multi-dimensional decoupled multi-scale U-Net for pancreatic cancer segmentation. [PDF]

PeerJ Comput Sci
Lu L, Wu M, Sen G, Ren F, Hu T.
europepmc   +1 more source

Prevalence of MUTYH Monoallelic Variants in Patients With Hereditary Cancer Using Multigene Panel Testing. [PDF]

Cancer Med
Caliendo G, Della Pepa C, Mignano A, Albanese L, Passariello L, Cozzolino A, Iengo F, Molinari AM, Pesce L, Vietri MT.   +9 more
europepmc   +1 more source

Implications of gut microbiota in hepatic and pancreatic diseases: Gut-liver-pancreas axis. [PDF]

World J Hepatol
Abdelwahab MM, Ghattas AS, Tawheed A.
europepmc   +1 more source