Results 101 to 110 of about 48,639 (314)

Isolated aneurysmal disease as an underestimated finding in individuals with JAG1 pathogenic variants

Human Mutation, Volume 43, Issue 12, Page 1824-1828, December 2022., 2022
Abstract Pathogenic variants in JAG1 are known to cause Alagille syndrome (ALGS), a disorder that primarily affects the liver, lung, kidney, and skeleton. Whereas cardiac symptoms are also frequently observed in ALGS, thoracic aortic aneurysms have only been reported sporadically in postmortem autopsies.
Jotte Rodrigues Bento, Alice Krebsová, Ilse Van Gucht, Irene Valdivia Callejon, An Van Berendoncks, Pavel Votypka, Ilse Luyckx, Petra Peldova, Steven Laga, Marek Havelka, Lut Van Laer, Pavel Trunecka, Nele Boeckx, Aline Verstraeten, Milan Macek, Josephina A. N. Meester, Bart Loeys   +16 more
wiley   +1 more source

Analysis of surgical volume and short‐term outcomes for upper gastrointestinal cancer post‐COVID‐19: Evidence from a nationwide Japanese database

Annals of Gastroenterological Surgery, EarlyView.
This study examined changes in surgical volume and short‐term outcomes for upper gastrointestinal cancer in the post‐COVID‐19 period using a nationwide Japanese database. We found that surgical treatments for gastrectomy and esophagectomy continued to be performed safely even after the COVID‐19 pandemic.
Masashi Takeuchi, Hideki Endo, Taizo Hibi, Ryo Seishima, Yusuke Takemura, Hiroyuki Yamamoto, Hiromichi Maeda, Akinobu Taketomi, Yoshihiro Kakeji, Yasuyuki Seto, Hideki Ueno, Masaki Mori, Ken Shirabe, Yuko Kitagawa   +13 more
wiley   +1 more source

Efficiency in Lung Transplant Allocation Strategies [PDF]

arXiv, 2018
Currently in the United States, lung transplantations are allocated to candidates according to the candidates' Lung Allocation Score (LAS). The LAS is an ad-hoc ranking system for patients' priorities of transplantation. The goal of this study is to develop a framework for improving patients' life expectancy over the LAS based on a comprehensive ...
arxiv  

Impact of hepatospleno volume ratio on postoperative chronic liver failure after major hepatectomy for perihilar cholangiocarcinoma

Annals of Gastroenterological Surgery, EarlyView.
The hepatospleno volume ratio and prealbumin levels 3 mo after major hepatectomy for perihilar cholangiocarcinoma are significant predictors of postoperative chronic liver failure (PCLF). The importance of this finding is that it emphasizes the need for targeted postoperative nutritional support and regular screening endoscopy to mitigate the risk of ...
Atsushi Takahashi, Yoshihiro Ono, Kosuke Kobayashi, Atsushi Oba, Takafumi Sato, Hiromichi Ito, Yosuke Inoue, Akio Saiura, Yu Takahashi   +8 more
wiley   +1 more source

MiniGPT-Pancreas: Multimodal Large Language Model for Pancreas Cancer Classification and Detection [PDF]

arXiv
Problem: Pancreas radiological imaging is challenging due to the small size, blurred boundaries, and variability of shape and position of the organ among patients. Goal: In this work we present MiniGPT-Pancreas, a Multimodal Large Language Model (MLLM), as an interactive chatbot to support clinicians in pancreas cancer diagnosis by integrating visual ...
arxiv  

Endocrine responses of type 1 (insulin-dependent) diabetic patients following successful pancreas transplantation [PDF]

, 1983
G. Pozza, J Traeger, J. M. Dubernard, Antonio Secchi, A. E. Pontiroli, Emanuele Bosi, Mohamed Malik, A Ruitton, N Blanc   +8 more
openalex   +1 more source

Clinical role of intraperitoneal chemotherapy in patients with pancreatic ductal adenocarcinoma concomitant with occult peritoneal dissemination: A multicenter retrospective study

Annals of Gastroenterological Surgery, EarlyView.
The effectiveness of intraperitoneal chemotherapy using paclitaxel (i.p.‐PTX) in pancreatic ductal adenocarcinoma (PDAC) patients with peritoneal dissemination remains elusive. This study indicated that the i.p.‐PTX therapy may improve survival in selected patients with PDAC, in particular those with occult peritoneal dissemination.
Tomohisa Yamamoto, Toshio Shimokawa, Masamichi Hayashi, Masamichi Mizuma, Katsuhisa Hirano, Atsushi Oba, Toshimichi Asano, Hideyo Miyato, Makoto Yoshida, Ippei Matsumoto, Yasunari Kawabata, Katsunori Sakamoto, Fuyuhiko Motoi, Shigeto Ishii, Yuki Homma, Hiromitsu Maehira, Yutaro Matsunaga, Tetsuya Ikemoto, Masafumi Nakamura, Yuko Mataki, Tsuyoshi Notake, Keiichi Akahoshi, Hideki Takami, So Yamaki, Daisuke Hashimoto, Yasutoshi Kimura, Satoshi Hirano, Yosuke Inoue, Tsutomu Fujii, Michiaki Unno, Yasuhiro Kodera, Joji Kitayama, Sohei Satoi, the Study Group of Pancreatic Ductal Adenocarcinoma with Peritoneal Dissemination   +33 more
wiley   +1 more source

Multicenter, prospective, observational study for urinary exosomal biomarkers of kidney allograft fibrosis

Scientific Reports
Severity of deceased donor kidney fibrosis impacts graft survival in deceased-donor kidney transplantation. Our aim was to identify potential miRNA biomarkers in urinary exosomes that mirror interstitial fibrosis and tubular atrophy (IFTA) severity ...
Mi Joung Kim, Hye Eun Kwon, Hye-Won Jang, Jin-Myung Kim, Jae Jun Lee, Joo Hee Jung, Youngmin Ko, Hyunwook Kwon, Young Hoon Kim, Heungman Jun, Sang Jun Park, Jun Gyo Gwon, Sung Shin   +12 more
doaj   +1 more source

Novel role of macrophage TXNIP-mediated CYLD–NRF2–OASL1 axis in stress-induced liver inflammation and cell death

JHEP Reports, 2022
Background & Aims: The stimulator of interferon genes (STING)/TANK-binding kinase 1 (TBK1) pathway is vital in mediating innate immune and inflammatory responses during oxidative/endoplasmic reticulum (ER) stress.
Yongqiang Zhan, Dongwei Xu, Yizhu Tian, Xiaoye Qu, Mingwei Sheng, Yuanbang Lin, Michael Ke, Longfeng Jiang, Qiang Xia, Fady M. Kaldas, Douglas G. Farmer, Bibo Ke   +11 more
doaj  

A weighted transplantation theorem for Jacobi coefficients [PDF]

arXiv, 2018
We present a transplantation theorem for Jacobi coefficients in weighted spaces. In fact, by using a discrete vector-valued local Calder\'{o}n-Zygmund theory, which has recently been furnished, we prove the boundedness of transplantation operators from $\ell^p(\mathbb{N},w)$ into itself, where $w$ is a weight in the discrete Muckenhoupt class $A_{p ...
arxiv