Results 91 to 100 of about 430,606 (268)

Deubiquitinating Enzyme: A Potential Secondary Checkpoint of Cancer Immunity

Frontiers in Oncology, 2020
The efficacy of cancer immunotherapy depends on the fine interplay between tumoral immune checkpoints and host immune system. However, the up-to-date clinical performance of checkpoint blockers in cancer therapy revealed that higher-level regulation ...
Xing Huang, Xing Huang, Xing Huang, Xiaozhen Zhang, Xiaozhen Zhang, Xiaozhen Zhang, Jian Xu, Jian Xu, Jian Xu, Xun Wang, Xun Wang, Xun Wang, Gang Zhang, Gang Zhang, Gang Zhang, Tianyu Tang, Tianyu Tang, Tianyu Tang, Xiaochao Shen, Xiaochao Shen, Xiaochao Shen, Tingbo Liang, Tingbo Liang, Tingbo Liang, Xueli Bai, Xueli Bai, Xueli Bai   +26 more
doaj   +1 more source

Hyper-Pairing Network for Multi-Phase Pancreatic Ductal Adenocarcinoma Segmentation [PDF]

arXiv, 2019
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with an overall five-year survival rate of 8%. Due to subtle texture changes of PDAC, pancreatic dual-phase imaging is recommended for better diagnosis of pancreatic disease. In this study, we aim at enhancing PDAC automatic segmentation by integrating multi-phase information (i ...
arxiv  

Pentraxin3 exacerbates acute pancreatitis injury by inhibiting oxidative phosphorylation pathway

Scientific Reports
Local pancreatic necrosis and systemic inflammatory response caused by acute pancreatitis (AP) are closely related to the disease prognosis and severity.
Wenyue Wang, Yaning Wang, Chenchen Yuan, Fei Cao, Weisong Tang, Qingtian Zhu, Xiaowu Dong, Lihui Deng, Guotao Lu, Qing Xia, Weiwei Chen   +10 more
doaj   +1 more source

Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes. [PDF]

, 2016
Type 1 diabetes (T1D) is caused by autoreactive T cells that recognize pancreatic islet antigens and destroy insulin-producing β-cells. This attack results from a breakdown in tolerance for self-antigens, which is controlled by ectopic antigen expression
Butte, Atul J, Fathman, C Garrison, Fuhlbrigge, Rebecca, Kodama, Keiichi, Miao, Dongmei, Toda, Kyoko, Yamada, Satoru, Yip, Linda, Yu, Liping, Zhao, Zhiyuan   +9 more
core   +1 more source

The Most Common Pancreatic Diseases [PDF]

, 2006
Akutni i kronični pankreatitis te karcinom gušterače tri su najčešće bolesti gušterače. U ovome preglednom članku prikazani su najvažniji epidemiološki, patofi ziološki i etiopatogenetski, ali i klinički, dijagnostički i terapijski elementi navedenih ...
Davor Štimac
core   +4 more sources

Cholangiocytes: Cell transplantation [PDF]

, 2017
Background:Due to significant limitations to the access to orthotropic liver transplantation, cell therapies forliver diseases have gained large interest worldwide.Scope of review:To revise current literature dealing with cell therapy for liver diseases.
Alvaro, Domenico, Bragazzi, MARIA CONSIGLIA, Cardinale, Vincenzo, Carpino, Guido, Gaudio, Eugenio, Ridola, Lorenzo   +5 more
core   +1 more source

World's longest surviving liver-pancreas recipient [PDF]

, 2007
In July 1988, the liver and pancreas of a cadaveric donor were transplanted separately into a man with type 1 diabetes with end-stage chronic hepatitis B virus.
Alessiani, Calne, Cecka, Farrell, Groth, Lillehei, Petruzzo, Philosophe, Pirenne, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stratta, Sutherland, Thai, Young   +20 more
core   +1 more source

Primary hyperparathyroidism can generate recurrent pancreatitis and secondary diabetes mellitus – A case report [PDF]

, 2019
Introduction. Acute or recurrent pancreatitis may be a complication of primary hyperparathyroidism and patients with previous episodes of pancreatitis may develop secondary diabetes mellitus. Case report.
Dănciulescu Miulescu, Rucsandra Elena, Guja, Loreta, Mîndrescu, Nicoleta, Văcaru, Georgeta, Ștefănescu, Emil   +4 more
core   +1 more source

Yes-associated protein (YAP) in pancreatic cancer: at the epicenter of a targetable signaling network associated with patient survival. [PDF]

, 2018
Pancreatic ductal adenocarcinoma (PDAC) is generally a fatal disease with no efficacious treatment modalities. Elucidation of signaling mechanisms that will lead to the identification of novel targets for therapy and chemoprevention is urgently needed ...
Eibl, Guido, Rozengurt, Enrique, Sinnett-Smith, James   +2 more
core   +2 more sources

Deep Distance Transform for Tubular Structure Segmentation in CT Scans [PDF]

arXiv, 2019
Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT scans is a challenging problem, due to issues such as poor contrast, noise and complicated background.
arxiv