Results 91 to 100 of about 461,778 (284)
ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells [PDF]
, 2016 The RhoA and RhoC GTPases act via the ROCK1 and ROCK2 kinases to promote actomyosin contraction, resulting in directly induced changes in cytoskeleton structures and altered gene transcription via several possible indirect routes.
Clark, William +3 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Pentraxin3 exacerbates acute pancreatitis injury by inhibiting oxidative phosphorylation pathway
Scientific ReportsLocal pancreatic necrosis and systemic inflammatory response caused by acute pancreatitis (AP) are closely related to the disease prognosis and severity.
Wenyue Wang +10 more
doaj +1 more source
Diagnosis of pancreatic disease in feline platynosomosis [PDF]
, 2017 Objectives: Platynosomum species are cat-specific parasitic trematodes that parasitize the biliary ducts and gall bladder. Due to the common connection to the major duodenal papilla of the pancreas and common bile ducts in addition to the periductal ...
Illanes, Oscar +4 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Clinical Analysis of Sinistral Portal Hypertension [PDF]
Iranian Journal of Medical SciencesBackground: Sinistral portal hypertension (SPH) is the only type of portal hypertension that is entirely curable. However, it can easily cause varicose veins in the esophagus and/or stomach, as well as upper gastrointestinal hemorrhage.
Jie Zheng, Gang Luo, Ming Ming Deng
doaj +1 more source
, 2017 In September, 10 advanced practice nurses from the Department of Surgery gathered for a lunchtime kick-off meeting to form a Nurse Practitioners (NPs) & Physician Assistants (PAs) Professionalism and Scholarship Working Group.
core +2 more sources
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Pancreatic function in children with non-alcoholic fatty pancreas disease
Zaporožskij Medicinskij Žurnal, 2019 Objective. To study the features of pancreatic function in children with pancreatic steatosis. Materials and methods. We examined 77 children; the average age of patients was (11.59 ± 2.82) years.
Yu. M. Stepanov +5 more
doaj +1 more source
Complex-based analysis of dysregulated cellular processes in cancer [PDF]
, 2014 Background: Differential expression analysis of (individual) genes is often used to study their roles in diseases. However, diseases such as cancer are a result of the combined effect of multiple genes.
Khanna, Kum Kum +6 more
core +1 more source