Results 141 to 150 of about 471,297 (330)

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Clock genes in pancreatic disease progression: from circadian regulation to dysfunction

Annals of Medicine
Background Circadian rhythms, governed by core clock genes, are essential for maintaining metabolic, endocrine, and immune homeostasis. Disruption of these rhythms has been increasingly implicated in the pathogenesis of various pancreatic diseases ...
Tiankuo Zheng, Kunpeng Wang, Qiao Shi, Lilong Zhang, Qihao Yan, Wanrong Jiang, Chen Chen, Kailiang Zhao, Jiarui Feng, Weixing Wang   +9 more
doaj   +1 more source

Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development. [PDF]

, 2019
Pancreatic ductal adenocarcinoma (PDAC) remains a deadly disease with no efficacious treatment options. PDAC incidence is projected to increase, which may be caused at least partially by the obesity epidemic.
Eibl, Guido, Rozengurt, Enrique
core  

PDX1‐MODY and dorsal pancreatic agenesis: New phenotype of a rare disease [PDF]

, 2017
Lílian Araújo Caetano, Lucas Santos de Santana, Aline Dantas Costa‐Riquetto, Antônio Marcondes Lerário, Márcia Nery, Gislaine Ferreira Nogueira, Consuelo Ortega, Manoel de Souza Rocha, Alexander A.L. Jorge, Milena Gurgel Teles   +9 more
openalex   +1 more source

Role of Fatty Acid Binding Protein 1 in Non- Alcoholic Fatty Pancreatic Disease with and without Diabetes Mellitus [PDF]

, 2023
Reda El Badawy, Awad M. Elabd, Mohamed Abdelmageed, Heba Bedair, Ghadeer Rashad   +4 more
openalex   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

Advanced Science, EarlyView.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang, Manli Wang, Yi Sun, Xiaoping Yue, Xun Li, Yanbing Lin, Geng Guo, Depeng Zhao, Qigang Fan, Xiaoling Ma, Zhihong Zhang, Shuaishuai Xing, Xiaoting Shen, Huidong Zhang   +13 more
wiley   +1 more source

Signifiance of autoimmune reactions to pancreatic juice in Crohn´s disease [PDF]

, 1988
Goebell, Harald, Malchow, H., Otte, M., Peskar, B. M., Scriba, Peter Christian, Stöcker, W.   +5 more
core   +1 more source

A Historical Perspective on Clinical Advances in Pancreatic Diseases [PDF]

, 2013
Anil K. Rustgi
openalex   +1 more source

Serum feline pancreatic lipase immunoreactivity and trypsin‐like immunoreactivity concentrations in cats with experimentally induced chronic kidney disease

, 2021
Panagiotis G. Xenoulis, Katerina T. Moraiti, Delmar R. Finco, Jan S. Suchodolski, Jörg M. Steiner   +4 more
openalex   +1 more source

Role of Retinol Binding Protein in Patients with Pancreatic Diseases [PDF]

, 2020
Л. В. Винокурова, K. A. Lesko, Д.С. Бордин, Ye.А. Dubtsova, Ye.Yu. Tyulyaeva, G.G. Varvanina   +5 more
openalex   +1 more source