Results 171 to 180 of about 461,778 (284)

Nutritional Support in Pancreatic Diseases. [PDF]

Nutrients, 2022
Cañamares-Orbís P, García-Rayado G, Alfaro-Almajano E.   +2 more
europepmc   +1 more source

Perioperative factors determine outcome after surgery for severe acute pancreatitis [PDF]

, 2004
De Waele, Jan, Hoste, Eric, Blot, Stijn, Hesse, Uwe, Pattyn, Piet, de Hemptinne, Bernard, Decruyenaere, Johan, Vogelaers, Dirk, Colardyn, Francis   +8 more
core   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Tube-bearing experience of patients with biliary and pancreatic diseases outside the hospital: based on qualitative study. [PDF]

BMC Gastroenterol
Liu J, Ye X, Chang S, Wu Z, Yuan B, Wang Q, Yao Y.   +6 more
europepmc   +1 more source

Changes in Pancreatic Senescence Mediate Pancreatic Diseases. [PDF]

Int J Mol Sci, 2023
Li K, Bian J, Xiao Y, Wang D, Han L, He C, Gong L, Wang M.   +7 more
europepmc   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Obesity and Pancreatic Diseases: From Inflammation to Oncogenesis and the Impact of Weight Loss Interventions. [PDF]

Nutrients
Souto M, Cúrdia Gonçalves T, Cotter J.
europepmc   +1 more source

PAR2: The Cornerstone of Pancreatic Diseases. [PDF]

Physiol Res, 2022
Suhaj P, Olejar T, Matej R.
europepmc   +1 more source

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

Phospholipase D2: A biomarker implicated in various pancreatic diseases beyond acute pancreatitis. [PDF]

World J Gastroenterol
Tornel Avelar AI, Gerrard CN, Priego Parra BA.   +2 more
europepmc   +1 more source