Results 281 to 290 of about 9,630,957 (406)

Underlying Disease Stress Augments Plasma and Tissue Adrenomedullin (AM) Responses to Endotoxin: Colocalized Increases in AM and Inducible Nitric Oxide Synthase within Pancreatic Islets [PDF]

, 1999
Ted H. Elsasser
openalex   +1 more source

The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism

Advanced Science, EarlyView.
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang, Yi Xie, Shenglong Xia, Xinnuo Ge, Jiaying Li, Fang Liu, Fan Jia, Shengyao Wang, Qiao Zhou, Menghan Gao, Weihuan Fang, Chao Zheng   +11 more
wiley   +1 more source

Quality of Life of Pediatric Patients with Chronic Intestinal, Liver, and Pancreatic Diseases During the COVID-19 Pandemic. [PDF]

Healthcare (Basel)
Dijmărescu I, Iordache AM, Păcurar D, Matran ER, Coroleucă A, Becheanu CA.   +5 more
europepmc   +1 more source

Pressure measurement from the biliary and pancreatic segments of the sphincter of Oddi: Comparison between patients with functional, biliary or pancreatic disease

, 1988
Hareth M. Raddawi, J. E. Geenen, Walter J. Hogan, W. J. Dodds, Rama P. Venu, G. Kenneth Johnson   +5 more
openalex   +1 more source

scHeteroNet: A Heterophily‐Aware Graph Neural Network for Accurate Cell Type Annotation and Novel Cell Detection

Advanced Science, EarlyView.
scHeteroNet) is a novel graph neural network model that explicitly addresses heterophily in single‐cell sequencing data enabling accurate cell type annotation and novel cell type discovery. By leveraging heterophily‐aware message passing and novelty propagation mechanisms, scHeteroNet achieves superior performance in both cell annotation and detection ...
Jiacheng Liu, Xingyu Fan, Chunbin Gu, Yaodong Yang, Bian Wu, Guangyong Chen, Chang‐Yu Hsieh, Pheng‐Ann Heng   +7 more
wiley   +1 more source

Public Fear of Pancreatic Diseases: Causes and Clinical Outcomes at a Single Korean Center. [PDF]

Gut Liver
Yoon WJ.
europepmc   +1 more source

Medical imaging for pancreatic diseases: Prediction of severe acute pancreatitis complicated with acute respiratory distress syndrome. [PDF]

World J Gastroenterol, 2022
Song LJ, Xiao B.
europepmc   +1 more source

Positive Feedback Regulation between KLF5 and XPO1 Promotes Cell Cycle Progression of Basal like Breast Cancer

Advanced Science, EarlyView.
KLF5 is highly expressed in BLBC patients and promotes Cyclin D1 and XPO1 transcription, ultimately leading to the inactivation of RB1. Both XPO1 inhibitor (KPT‐330) and CDK4/6 inhibitor (Palbociclib) can enhance RB1 activity and exert antitumor effects. It has been proved that the combination of KPT‐330 and Palbociclib can inhibit the proliferation of
Yu Tang, Rui Liu, Jing Zhu, Qian He, Chenglong Pan, Zhongmei Zhou, Jian Sun, Fubing Li, Longlong Zhang, Yujie Shi, Jing Yao, Dewei Jiang, Ceshi Chen   +12 more
wiley   +1 more source

Sedative effects of propofol and risk factors for excessive sedation in the endoscopic treatment of biliary and pancreatic diseases. [PDF]

DEN Open
Maruki Y, Hijioka S, Yagi S, Takasaki T, Chatto M, Fukuda S, Yamashige D, Okamoto K, Agarie D, Hara H, Hagiwara Y, Nagashio Y, Morizane C, Sone M, Okusaka T, Saito Y.   +15 more
europepmc   +1 more source

Applications of endoscopic ultrasound elastography in pancreatic diseases: From literature to real life. [PDF]

World J Gastroenterol, 2022
Conti CB, Mulinacci G, Salerno R, Dinelli ME, Grassia R.   +4 more
europepmc   +1 more source