Results 301 to 310 of about 9,818,371 (382)

Variations of oral microbiota are associated with pancreatic diseases including pancreatic cancer

Gut, 2011
J. Farrell, Lei Zhang, Hui Zhou, D. Chia, D. Elashoff, David Akin, B. Paster, K. Joshipura, D. Wong   +8 more
semanticscholar   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang, Xueying Wang, Shanhong Lu, Yan Gao, Gangcai Zhu, Guo Li, Zongnan Yu, Junwei Hou, Helei Yan, Wenhui Yuan, Xin Zhang, Mien‐Chie Hung, Zhifeng Liu, Yong Liu   +13 more
wiley   +1 more source

Exploring the Associations of Inflammatory and Oxidative Stress Biomarkers with Pancreatic Diseases: An Observational and Mendelian Randomisation Study. [PDF]

J Clin Med
Vilà-Quintana L, Fort E, Pardo L, Albiol-Quer MT, Ortiz MR, Capdevila M, Feliu A, Bahí A, Llirós M, Aguilar E, García-Velasco A, Ginestà MM, Laquente B, Pozas D, Lluansí A, Pimenoff VN, Moreno V, Garcia-Gil LJ, Duell EJ, Carreras-Torres R, Aldeguer X.   +20 more
europepmc   +1 more source

CYTOKINES AND DISTRIBUTION OF IMMUNE CELLS IN PATIENTS WITH SURGICAL HEPATOBILIARY-PANCREATIC (HBP) DISEASE WITH AND WITHOUT JAUNDICE

, 1999
Mikael Ljungdahl, Johanna Österberg, U Haglund   +2 more
openalex   +1 more source

UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis

Advanced Science, EarlyView.
These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang, Lilong Zhang, Beiying Deng, Wanrong Jiang, Tianrui Kuang, Chen Chen, Kailiang Zhao, Qiao Shi, Jun He, Weixing Wang   +9 more
wiley   +1 more source

Bibliometric analysis of pancreatic diseases and gut microbiota research from 2002 to 2022. [PDF]

Heliyon
Li X, Li Y, He C, Zhu Y.
europepmc   +1 more source

Prospective, Randomized Trial of Octreotide to Prevent Pancreatic Fistula After Pancreaticoduodenectomy for Malignant Disease

, 1997
Andrew M. Lowy, Jeffrey E. Lee, Peter W. T. Pisters, Bradley S. Davidson, Claudia J. Fenoglio, Pam Stanford, Rashida Jinnah, Douglas B. Evans   +7 more
openalex   +2 more sources

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

The Role of Endocrine Disruption Chemical-Regulated Aryl Hydrocarbon Receptor Activity in the Pathogenesis of Pancreatic Diseases and Cancer. [PDF]

Int J Mol Sci
Kim K.
europepmc   +1 more source

The pancreatic stellate cell: a star on the rise in pancreatic diseases.

Journal of Clinical Investigation, 2007
M. B. Omary, Anson W. Lowe, S. Pandol, A. Lugea   +3 more
semanticscholar   +1 more source