Results 51 to 60 of about 2,622,204 (301)

Laparoscopic radical distal pancreatosplenectomy with celiac axis excision following neoadjuvant chemotherapy for locally advanced pancreatic cancer [PDF]

, 2022
A recent successful prospective randomized control study comparing open distal pancreatectomy with laparoscopic distal pancreatectomy (LDP) has shown that LDP is a safe and effective surgical modality in treating left-sided pancreatic pathological ...
황호경, 강창무, 김성현, 이우정, 김지수   +4 more
core   +1 more source

Selective occlusion of the hepatic artery and portal vein improves liver hypertrophy for staged hepatectomy

World Journal of Surgical Oncology, 2019
Background To evaluate the safety and feasibility of selective occlusion of the hepatic artery and portal vein (SOAP) for staged hepatectomy (SOAPS) in patients with hepatocellular carcinoma (HCC) Methods From December 2014 to August 2018, 9 patients ...
Changku Jia, Ke Ge, Sunbing Xu, Ling Liu, Jie Weng, Youke Chen   +5 more
doaj   +1 more source

Immunity-Related Gene Signature Identifies Subtypes Benefitting From Adjuvant Chemotherapy or Potentially Responding to PD1/PD-L1 Blockage in Pancreatic Cancer

Frontiers in Cell and Developmental Biology, 2021
Tumor microenvironment comprises of a variety of cell types, which is quite complex and involved in chemotherapy and immune checkpoint blockage resistance.
Hao Qian, Hao Qian, Hongzhe Li, Hongzhe Li, Junjie Xie, Junjie Xie, Xiongxiong Lu, Xiongxiong Lu, Fanlu Li, Fanlu Li, Weishen Wang, Weishen Wang, Xiaomei Tang, Xiaomei Tang, Minmin Shi, Minmin Shi, Linxi Jiang, Linxi Jiang, Hongwei Li, Hongwei Li, Hao Chen, Hao Chen, Chenghong Peng, Chenghong Peng, Zhiwei Xu, Zhiwei Xu, Xiaxing Deng, Xiaxing Deng, Baiyong Shen, Baiyong Shen, Baiyong Shen, Baiyong Shen   +31 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

The Role of Bile in the Regulation of Exocrine Pancreatic Secretion [PDF]

, 1992
As early as 1926 Mellanby (1) was able to show that introduction of bile into the duodenum of anesthetized cats produces a copious flow of pancreatic juice.
Riepl, Rudolf L., Lehnert, Peter
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

A case of pancreatic hamartoma pathologically confirmed after robot-assisted pancreaticoduodenectomy [PDF]

, 2019
Pancreatic hamartoma is a rare benign tumor that can be easily misdiagnosed due to its rarity. Its diagnostic ambiguity demands surgical resection for confirmation.
황호경, 노승윤, 강창무, 이우정   +3 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Risk factors for suicide in patients with pancreatic ductal adenocarcinoma: A population‐based study

Aging and Cancer
Background Patients diagnosed with pancreatic ductal adenocarcinoma (PDAC) face a notable risk of suicide. However, comprehensive population‐based studies on suicide risk in PDAC patients have been lacking. This study seeks to explore the suicide risk in
Chao Wang, Haoda Chen, Yuanchi Weng, Xiaxing Deng, Weishen Wang, Baiyong Shen   +5 more
doaj   +1 more source