CT Evaluation of Acute Pancreatitis and its Prognostic Correlation with CT Severity Index [PDF]
Journal of Clinical and Diagnostic Research, 2016 Introduction: Pancreatitis is one of most complex and clinically challenging of all abdominal disorders. USG and abdominal CT are the most commonly used diagnostic imaging modalities for the evaluation of pancreas.
Sameer Raghuwanshi +3 more
doaj +1 more source
Automatic Endoscopic Ultrasound Station Recognition with Limited Data [PDF]
arXiv, 2023 Pancreatic cancer is a lethal form of cancer that significantly contributes to cancer-related deaths worldwide. Early detection is essential to improve patient prognosis and survival rates. Despite advances in medical imaging techniques, pancreatic cancer remains a challenging disease to detect.
arxiv
β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. [PDF]
, 2010 ObjectiveThe islet in type 2 diabetes is characterized by β-cell apoptosis, β-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP).
Butler, Alexandra E +7 more
core +2 more sources
Progress of Pancreatic Stellate Cells in Research of Pancreatic Disease Model
Shiyan dongwu yu bijiao yixue, 2022 Common types of pancreatic diseases are pancreatitis, diabetes and pancreatic cancer. Clinical studies have found that pancreatic stellate cells (PSCs) in patients with pancreatic diseases, contributes to fibrosis, oxidative stress and inflammation, and ...
WEI Xun +4 more
doaj +1 more source
Tumorigenesis and axons regulation for the pancreatic cancer: a mathematical approach [PDF]
arXiv, 2022 The nervous system is today recognized to play an important role in the development of cancer. Indeed, neurons extend long processes (axons) that grow and infiltrate tumors in order to regulate the progression of the disease in a positive or negative way, depending on the type of neuron considered.
arxiv
Gene targeting in disease networks [PDF]
arXiv, 2021 Profiling of whole transcriptomes has become a cornerstone of molecular biology and an invaluable tool for the characterization of clinical phenotypes and the identification of disease subtypes. Analyses of these data are becoming ever more sophisticated as we move beyond simple comparisons to consider networks of higher-order interactions and ...
arxiv
The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant [PDF]
, 2020 One of the most common mutations in the serine protease inhibitor Kazal type 1 (SPINK1) gene is the N34S variant which is strongly associated with chronic pancreatitis. Although it is assumed that N34S mutation constitutes a high-risk factor, the underlying pathologic mechanism is still unknown.
arxiv +1 more source
Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice. [PDF]
, 2019 We examined the impact of statins on Yes-associated Protein (YAP) localization, phosphorylation and transcriptional activity in human and mouse pancreatic ductal adenocarcinoma (PDAC) cells.
Chang, Hui-Hua +7 more
core +2 more sources
Obesity and Pancreatic Diseases
The Korean Journal of Gastroenterology, 2012 Obesity is defined as BMI (calculated as weight in kg divided by height in m2) more than 30, and overweight is defined as BMI of 25-29.9. Obesity has been considered as a risk factor for pancreatic diseases, including pancreatitis and pancreatic cancer. Severe acute pancreatitis is significantly more frequent in obese patients.
Ho Gak Kim, Jimin Han
openaire +2 more sources
Laboratory diagnosis of pancreatic diseases
Клинический разбор в общей медицине, 2022 Diseases of the pancreas in diagnosis are very problematic, since the symptoms are non-specific, and the training of doctors in the field of clinical pancreatology leaves much to be desired. With a incidence of 3–4/100 000 inhabitants and a prevalence of
Ekaterina Yu. Plotnikova
doaj +1 more source