Results 101 to 110 of about 130,783 (232)

SLC39A1 contributes to gemcitabine resistance of pancreatic ductal adenocarcinoma by activating AMPK signaling

open access: yesBangladesh Journal of Pharmacology
Gemcitabine is a common first-line chemotherapy agent, but gemcitabine resistance is a clinical challenge for pancreatic ductal adenocarcinoma patients.
Hao Yu   +5 more
doaj   +1 more source

MicroRNAs in pancreatic ductal adenocarcinoma

open access: yesWorld Journal of Gastroenterology, 2011
Ductal adenocarcinoma of the pancreas is a lethal cancer for which the only chance of long-term survival belongs to the patient with localized disease in whom a potentially curative resection can be done. Therefore, biomarkers for early detection and new therapeutic strategies are urgently needed.
Jong Y, Park   +5 more
openaire   +2 more sources

The Potential for Circulating Tumor Cells in Pancreatic Cancer Management. [PDF]

open access: yes, 2017
Pancreatic cancer is one the most lethal malignancies. Only a small proportion of patients with this disease benefit from surgery. Chemotherapy provides only a transient benefit.
Michael Pimienta   +4 more
core   +2 more sources

Pancreas 3D Organoids: Current and Future Aspects as a Research Platform for Personalized Medicine in Pancreatic Cancer

open access: yesCellular and Molecular Gastroenterology and Hepatology, 2018
Pancreatic ductal adenocarcinoma is one of the most aggressive forms of cancer, and the third leading cause of cancer-related mortality in the United States.
Leticia Moreira   +5 more
doaj   +1 more source

Overall survival of patients with recurrent pancreatic cancer treated with systemic therapy: a retrospective study [PDF]

open access: yes, 2019
BACKGROUND: Only a few patients with pancreatic ductal adenocarcinoma (PDAC) recurring after curative resection and peri-operative (neoadjuvant and adjuvant) therapy are included in clinical trials of metastatic PDAC.
Gbolahan, Olumide B.   +4 more
core   +1 more source

Diabetic ketoacidosis as the presenting manifestation of pancreatic adenocarcinoma with cystic features

open access: yesTurkish Journal of Emergency Medicine, 2017
The common presenting symptoms of pancreatic cancer are abdominal pain, weight loss, and jaundice. Pancreatic adenocarcinoma presenting with diabetic ketoacidosis is a very rare emergent clinical condition.
Tezcan Kaya   +4 more
doaj   +1 more source

Diminishing calcifications as a potential predictor of pancreatic ductal adenocarcinoma arising in association with IPMN in patients with chronic pancreatitis

open access: yesRadiology Case Reports
Chronic pancreatitis (CP) is a progressive benign fibroinflammatory condition involving repeated episodes of pancreatic inflammation, which lead to fibrotic tissue replacement and subsequent pancreatic insufficiency.
Mohammad Yasrab, MD   +8 more
doaj   +1 more source

Diffusion-weighted MR imaging of pancreatic cancer: A comparison of mono-exponential, bi-exponential and non-Gaussian kurtosis models

open access: yesEuropean Journal of Radiology Open, 2016
Objectives: To compare two Gaussian diffusion-weighted MRI (DWI) models including mono-exponential and bi-exponential, with the non-Gaussian kurtosis model in patients with pancreatic ductal adenocarcinoma.
Nikolaos Kartalis   +7 more
doaj   +1 more source

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