Role of Adjuvant Chemotherapy in Distal Cholangiocarcinoma
Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.ABSTRACT Background Recent studies addressing the role of adjuvant chemotherapy (AC) in cholangiocarcinoma (CCA) have been published; however, there are challenges in generalizing the findings due to different prognostic characteristics depending on tumor location and resectability.
Yoon Soo Chae +9 more
wiley +1 more source
Expression of Ki-67, p53, and K-ras in chronic pancreatitis and pancreatic ductal adenocarcinoma
, 2005 Seok Jeong
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Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.ABSTRACT Background and Study Aim Endoscopic papillectomy (EP) is widely performed for avoiding high‐risk surgeries. However, recurrence rates are high, and lateral extension is a risk for recurrence. With endoscopic submucosal dissection (ESD), even lesions with lateral extensions are able to be en bloc resected, and may reduce that risk.
Takashi Hirose +9 more
wiley +1 more source
Expression of a prometastatic splice variant of osteopontin, OPNC, in human pancreatic ductal adenocarcinoma [PDF]
, 2009 Jennifer L. Sullivan +11 more
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Journal of Surgical Oncology, EarlyView.ABSTRACT Background Gastroenteropancreatic neuroendocrine tumors (GEP‐NETs) are a rare and biologically diverse group of tumors that are challenging to image. 68Ga‐DOTATATE PET/CT is the most sensitive imaging tool for these tumors, and while its use has increased over time, its clinical impact remains unclear, particularly for clinical scenarios ...
Orjola Prela +8 more
wiley +1 more source
Alterations in the Smad4 gene in hamster pancreatic duct adenocarcinomas and established cell lines
, 2006 Kyoko Shimizu +6 more
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Sequence of Chemotherapy May Not Impact Survival After Resection of Pancreatic Tail Adenocarcinoma
Journal of Surgical Oncology, EarlyView.ABSTRACT Introduction Pancreatic ductal adenocarcinoma (PDAC) of the body/tail is notably different than PDAC in the head of the pancreas. Surgery plus chemotherapy is known to improve outcomes for all PDAC. The sequence of this therapy is well studied in head cancers yet has never been evaluated systematically in relation to distal pancreatectomy (DP).
Chase J. Wehrle +12 more
wiley +1 more source
A Preliminary Study on the Therapeutic Role of γδT Cells in Triple‐Negative Breast Cancer
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT This study was aimed to elucidate the cytotoxic effects of γδT cells on triple‐negative breast cancer (TNBC) cells and assess their antitumor efficacy in a mouse xenograft model. Furthermore, the underlying mechanisms of γδT cell action on TNBC were explored.
Shi Qiu +4 more
wiley +1 more source
An integrated humoral and cellular response is elicited in pancreatic cancer by α‐enolase, a novel pancreatic ductal adenocarcinoma‐associated antigen [PDF]
, 2009 Paola Cappello +15 more
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Human Organoids and Their Application in Tumor Models, Disease Modeling, and Tissue Engineering
Medicine Bulletin, EarlyView.ABSTRACT Organoid technology has revolutionized biomedical research, disease modeling, drug discovery, and regenerative medicine by providing three‐dimensional (3D) organ‐like structures that closely mimic native human tissues. Derived from pluripotent and adult stem cells, organoids replicate the structural, cellular, and functional characteristics of
Siyuan Song, Zheng Liu, Yi Wang, Bo Gong
wiley +1 more source