Results 261 to 270 of about 231,974 (295)

Perineural Invasion Reprograms the Immune Microenvironment through Cholinergic Signaling in Pancreatic Ductal Adenocarcinoma

Cancer Research, 2020
These findings provide a promising therapeutic strategy to modulate the immunosuppressive microenvironment of pancreatic ductal adenocarcinoma with severe perineural invasion.
Min-Wei Yang, Lingye Tao, Yong-sheng Jiang, JianYu Yang, Y. Huo, De-Jun Liu, Jiao Li, Xueliang Fu, Ruizhe He, Chaoyi Lin, Wei Liu, Jun-Feng Zhang, R. Hua, Qing Li, Shuheng Jiang, Lipeng Hu, Guang-Ang Tian, Xiao-Xin Zhang, Ningning Niu, P. Lu, Juanjuan Shi, G. Xiao, Li-wei Wang, J. Xue, Zhi-gang Zhang, Yong-wei Sun   +25 more
semanticscholar   +1 more source

Genomics of pancreatic ductal adenocarcinoma

Hepatobiliary & Pancreatic Diseases International, 2014
Pancreatic cancer is one of the worst prognostic cancers because of the late diagnosis and the absence of effective treatment. Within all subtypes of this disease, ductal adenocarcinoma has the shortest survival time. In recent years, global genomics profiling allowed the identification of hundreds of genes that are perturbed in pancreatic cancer.
Christian, Pilarsky, Robert, Grutzmann
openaire   +2 more sources

Hypoxia and pancreatic ductal adenocarcinoma

Cancer Letters, 2020
Chemotherapy and immunotherapy for pancreatic ductal adenocarcinoma (PDAC) have limited success. One reason for this is thought to be the cancer microenvironment surrounding PDAC. Hypoxia is a feature of the cancer microenvironment. Under hypoxia, different various molecules and signaling pathways are activated compared with normoxia.
Akio, Yamasaki, Kosuke, Yanai, Hideya, Onishi   +2 more
openaire   +2 more sources

Surgery for pancreatic ductal adenocarcinoma

Clinical and Translational Oncology, 2017
Surgical resection is the only potentially curative option in the treatment of pancreatic ductal adenocarcinoma. Preoperative radiological imaging allows to rule out the presence of metastases. Three resectability categories are established based on the radiological findings depending on the degree of contact between the tumor and the blood vessels ...
R. Vera, L. Díez, E. Martín Pérez, J. C. Plaza, A. Sanjuanbenito, A. Carrato   +5 more
openaire   +2 more sources

Pancreatic Resection for M1 Pancreatic Ductal Adenocarcinoma

Annals of Surgical Oncology, 2006
Improved safety of pancreatic surgery has led to consideration of more aggressive approaches, such as resection for primary pancreatic ductal adenocarcinoma (PDAC) with metastatic disease (M1).A total of 29 patients who underwent pancreatic resection with resection of associated metastatic disease (interaortocaval lymph node dissection, liver resection,
Shailesh V, Shrikhande, Jörg, Kleeff, Carolin, Reiser, Jürgen, Weitz, Ulf, Hinz, Irene, Esposito, Jan, Schmidt, Helmut, Friess, Markus W, Büchler   +8 more
openaire   +2 more sources

Pancreatic Ductal Adenocarcinoma Derived From IPMN and Pancreatic Ductal Adenocarcinoma Concomitant With IPMN

Pancreas, 2011
Pancreatic ductal adenocarcinoma (PDAC) may derive from an intraductal papillary mucinous neoplasm (IPMN) of the pancreas or may develop in the pancreatic duct apart from IPMN. The purpose of this study was to define the clinicopathological features of these 2 entities and compare them with those of ordinary PDAC.Of 765 patients who had surgical ...
Koji, Yamaguchi, Shuichi, Kanemitsu, Takashi, Hatori, Hiroyuki, Maguchi, Yasuhiro, Shimizu, Minoru, Tada, Toshio, Nakagohri, Keiji, Hanada, Manabu, Osanai, Yutaka, Noda, Akihiko, Nakaizumi, Toru, Furukawa, Shinichi, Ban, Bunsei, Nobukawa, Yo, Kato, Masao, Tanaka   +15 more
openaire   +2 more sources

BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma

Nature Cell Biology, 2020
Jin-Tao Li, M. Yin, Di Wang, Jian Wang, Ming-Zhu Lei, Ye Zhang, Y. Liu, Lei Zhang, Shao-wu Zou, Lipeng Hu, Zhi-gang Zhang, Yi-Ping Wang, Wenyan Wen, Hao-Jie Lu, Zhengju Chen, Dan Su, Q. Lei   +16 more
semanticscholar   +1 more source

Pancreatic Ductal Adenocarcinoma

2023
Anushri Parakh, Yoshifumi Noda, Avinash R. Kambadakone, Dushant V. Sahani   +3 more
openaire   +1 more source

Pancreatic Ductal Adenocarcinoma

2004
Michael Bouvet, Jeannie Shen, A.R. Moossa   +2 more
openaire   +1 more source

Learning to distinguish progressive and non-progressive ductal carcinoma in situ

Nature Reviews Cancer, 2022
Mathilde Matthea Machteld Almekinders, Charlotta Mulder, Deborah Collyar   +2 more
exaly