Results 261 to 270 of about 64,777 (328)

The oncogenic kinase Pim-1 is modulated by K-Ras signaling and mediates transformed growth and radioresistance in human pancreatic ductal adenocarcinoma cells [PDF]

, 2011
Dapeng Xu, Stephen A. Allsop, Sam M. Witherspoon, John L. Snider, Jen Jen Yeh, James J. Fiordalisi, C D White, Daniel R. Williams, Adrienne D. Cox, Antonio T. Baines   +9 more
openalex   +1 more source

A clinically feasible multiplex proteomic immunoassay as a novel functional diagnostic for pancreatic ductal adenocarcinoma [PDF]

, 2017
Azar, Riad R, Cao, Dengfeng, Early, Dayna S, et al,, Gao, Feng, Kushnir, Vladamir M, Li, Lin, Lim, Kian-Huat, Luo, Jingqin, Mullady, Daniel K, Wang-Gillam, Andrea   +10 more
core   +2 more sources

Neoadjuvant Chemotherapy With Chemoradiotherapy for Patients With Borderline Resectable or Locally Advanced Pancreatic Ductal Adenocarcinoma— Retrospective Review From a Tertiary Care Hospital

Asia-Pacific Journal of Clinical Oncology, EarlyView.
A single‐centre retrospectively analyzed 37 BRPC/LAPC patients receiving neoadjuvant chemotherapy ± chemoradiotherapy. Surgical resection was feasible in 62% of patients, with 38% of patients achieving R0 resections. The median overall survival was 21 months, and disease‐free survival was 12.7 months.
Avtaj Nerwal, Desmond Yip, Sivakumar Gananadha, Amy Shorthouse, Belinda Lee, Ankit Jain   +5 more
wiley   +1 more source

Pancreatic Ductal Adenocarcinomas in Long-Term Follow-Up Patients With Branch Duct Intraductal Papillary Mucinous Neoplasms

, 2009
Satoshi Tanno, Yasuhiro Nakano, Kazuya Koizumi, Yoshiaki Sugiyama, Kazumasa Nakamura, Junpei Sasajima, Tomoya Nishikawa, Yusuke Mizukami, Nobuyuki Yanagawa, Tsuneshi Fujii, Toshikatsu Okumura, Takeshi Obara, Yutaka Kohgo   +12 more
openalex   +2 more sources

Basophil Activation Test: Bridging Allergy and Oncology for Diagnostic, Therapeutic and Prognostic Applications in AllergoOncology: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT The basophil activation test (BAT) is gaining increasing relevance as an ex vivo functional assay in allergy to evaluate IgE‐mediated hypersensitivity reactions to food allergens, venoms, and drugs and to monitor tolerance induction. Establishing universal standard operating protocols has been difficult, due to several challenges including ...
Mariona Pascal, Jitesh Chauhan, Edward Knol, Rodolfo Bianchini, Mariana Castells, Leticia De las Vecillas, Karin Hartmann, Elena Izquierdo, Uta Jappe, Teodorikez‐Wilfox Jimenez‐Rodriguez, Francesca Levi‐Schaffer, Cristobalina Mayorga, Aurélie Poli, Frank Redegeld, Alexandra F. Santos, Erika Jensen‐Jarolim, Christoph Bergmann, Sophia N. Karagiannis, Heather J. Bax   +18 more
wiley   +1 more source

First application of three‐dimensional light sheet fluorescence microscopy to human testicular tumors: New perspectives in histopathology

Andrology, EarlyView.
Abstract Background Testicular tumors are among the most frequently diagnosed cancers in young men. The consequences of this diagnosis are orchiectomies, severely restricting fertility. For these young patients, a comprehensive diagnostics would be desirable, achieving a refined diagnosis and improved therapeutic patient stratification.
Diana Pinkert‐Leetsch, Ahmad Kareem, Simon F. Merz, Marc Teckentrup, Alexander Fichtner, Felix Bremmer, Jeannine Missbach‐Guentner   +6 more
wiley   +1 more source

Decreased Expression of Angiotensin-Converting Enzyme 2 in Pancreatic Ductal Adenocarcinoma Is Associated with Tumor Progression

, 2009
Lin Zhou, Ruifeng Zhang, Weiyan Yao, Jiancheng Wang, Aihua Qian, Min-min Qiao, Yongping Zhang, Yaozong Yuan   +7 more
openalex   +2 more sources

Opportunities of patient‐derived organoids in drug development

British Journal of Pharmacology, EarlyView.
Various model systems are utilised during drug development starting from basic research, moving to preclinical research and development for clinical applications in order to identify new drugs to improve human health. However, there are characteristics of humans that are not captured by established models.
Antonia Büning, Elena Reckzeh
wiley   +1 more source

Pancreatic cancer - invasive ductal adenocarcinoma

, 2009
Mostafa El-Feky, Natalie Yang
openalex   +1 more source

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng, Jasper F. Ooms, Erik H. J. Danen, Laura H. Heitman   +3 more
wiley   +1 more source