Results 261 to 270 of about 217,476 (395)

Insulin‐Like Growth Factor 1 Receptor Expression for Predicting PD‑1/PD‑L1 Inhibitor Response in Hypopharyngeal Squamous Cell Carcinoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Insulin‐like growth factor 1 receptor (IGF‐1R) is crucial for immunological control and the development of different types of cancer. It is still uncertain how the expression of IGF‐1R impacts hypopharyngeal squamous cell carcinoma (HPSCC) and whether it has any predictive value for prognosis.
Wen‐Jing Li   +10 more
wiley   +1 more source

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang   +12 more
wiley   +1 more source

DNA Damage Repair Defects and Survival Outcomes for Patients With Resected Pancreatic Ductal Adenocarcinoma

open access: green, 2021
Amy Chang   +10 more
openalex   +2 more sources

Does Adjuvant Therapy in Invasive Intraductal Papillary Mucinous Neoplasm of the Pancreas Improve Survival? A Systematic Review and Meta‐Analysis Using Trial Sequential Analysis

open access: yesWorld Journal of Surgery, EarlyView.
Question: What is the efficacy of adjuvant therapy in resected invasive IPMN? Findings: This meta‐analysis showed that patients with invasive IPMN do not benefit from adjuvant therapy (HR 1.21, 95% IC: 0.81−1.79). A subgroup analysis showed that node‐positive patients have an improved OS (HR 1.86; 95% CI 1.39; 2.47, p < 0.001).
Carlo Ingaldi   +9 more
wiley   +1 more source

Defining an Unresectable Primary Retroperitoneal Sarcoma

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background Retroperitoneal sarcomas (RPS) comprise a heterogenous group of rare mesenchymal tumours. A complete macroscopic en bloc resection of the tumour with involved adjacent structures is the only curative treatment modality. There remain no consensus criteria regarding the definition of a resectable versus unresectable RPS.
James Tai   +6 more
wiley   +1 more source

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