Results 271 to 280 of about 84,601 (303)
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Hypoxia and pancreatic ductal adenocarcinoma
Cancer Letters, 2020Chemotherapy and immunotherapy for pancreatic ductal adenocarcinoma (PDAC) have limited success. One reason for this is thought to be the cancer microenvironment surrounding PDAC. Hypoxia is a feature of the cancer microenvironment. Under hypoxia, different various molecules and signaling pathways are activated compared with normoxia.
Akio, Yamasaki +2 more
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Genomics of pancreatic ductal adenocarcinoma
Hepatobiliary & Pancreatic Diseases International, 2014Pancreatic cancer is one of the worst prognostic cancers because of the late diagnosis and the absence of effective treatment. Within all subtypes of this disease, ductal adenocarcinoma has the shortest survival time. In recent years, global genomics profiling allowed the identification of hundreds of genes that are perturbed in pancreatic cancer.
Christian, Pilarsky, Robert, Grutzmann
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Surgery for pancreatic ductal adenocarcinoma
Clinical and Translational Oncology, 2017Surgical resection is the only potentially curative option in the treatment of pancreatic ductal adenocarcinoma. Preoperative radiological imaging allows to rule out the presence of metastases. Three resectability categories are established based on the radiological findings depending on the degree of contact between the tumor and the blood vessels ...
R. Vera +5 more
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Pancreatic Ductal Adenocarcinoma
2018Objective: Patients who undergo an R0 resection of their pancreatic ductal adenocarcinoma (PDAC) have an improved survival compared with patients who undergo an R1 resection. It is unclear whether an R1 resection confers a survival benefit over locally advanced (LA) unresectable tumors.
Konstantinidis, Ioannis T +12 more
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Pancreatic Resection for M1 Pancreatic Ductal Adenocarcinoma
Annals of Surgical Oncology, 2006Improved safety of pancreatic surgery has led to consideration of more aggressive approaches, such as resection for primary pancreatic ductal adenocarcinoma (PDAC) with metastatic disease (M1).A total of 29 patients who underwent pancreatic resection with resection of associated metastatic disease (interaortocaval lymph node dissection, liver resection,
Shailesh V, Shrikhande +8 more
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Pancreas, 2011
Pancreatic ductal adenocarcinoma (PDAC) may derive from an intraductal papillary mucinous neoplasm (IPMN) of the pancreas or may develop in the pancreatic duct apart from IPMN. The purpose of this study was to define the clinicopathological features of these 2 entities and compare them with those of ordinary PDAC.Of 765 patients who had surgical ...
Koji, Yamaguchi +15 more
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Pancreatic ductal adenocarcinoma (PDAC) may derive from an intraductal papillary mucinous neoplasm (IPMN) of the pancreas or may develop in the pancreatic duct apart from IPMN. The purpose of this study was to define the clinicopathological features of these 2 entities and compare them with those of ordinary PDAC.Of 765 patients who had surgical ...
Koji, Yamaguchi +15 more
openaire +2 more sources
Proteogenomic characterization of pancreatic ductal adenocarcinoma
Cell, 2021Liwei Cao, Chen Huang, Daniel Cui Zhou
exaly
Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma
Ca-A Cancer Journal for Clinicians, 2020Aaron J Grossberg +2 more
exaly
Gemcitabine resistance in pancreatic ductal adenocarcinoma
Drug Resistance Updates, 2015Yoav Binenbaum +2 more
exaly