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Aquaporins in pancreatic ductal adenocarcinoma

APMIS, 2021
Aquaporins are water channel proteins facilitating passive transport of water across cellular membranes. Aquaporins are over‐ or ectopically expressed in a multitude of cancers, including pancreatic ductal adenocarcinoma, which is a highly aggressive cancer with low survival rate. Evidence suggests that aquaporins can affect multiple cellular processes
Anne Sofie, Bruun-Sørensen, Sarannya, Edamana, Frédéric H, Login, Signe, Borgquist, Lene N, Nejsum   +4 more
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Immunotherapy for pancreatic ductal adenocarcinoma

Journal of Surgical Oncology, 2021
AbstractPancreatic ductal adenocarcinoma (PDAC) remains a lethal cancer with an urgent need for better medical therapies. Efforts have been made to investigate the efficacy of immunotherapy, particularly given the hallmarks of immune suppression and exhaustion in PDAC tumors.
Eileen Carpenter, Sarah Nelson, Filip Bednar, Clifford Cho, Hari Nathan, Vaibhav Sahai, Marina Pasca di Magliano, Timothy L. Frankel   +7 more
openaire   +2 more sources

Microbiome and pancreatic ductal adenocarcinoma

Clinics and Research in Hepatology and Gastroenterology, 2021
Pancreatic ductal adenocarcinoma (PDAC) incidence and related-deaths are increasing worldwide. PDAC is characterized by poor prognosis due to late diagnosis, high metastatic capacity and resistance to therapy. This is partially due to its specific microenvironment, where the stroma is prominent over tumor cells. Besides the oral and gut microbiota, the
Annemilaï Tijeras-Raballand, Marc Hilmi, Lucile Astorgues-Xerri, Rémy Nicolle, Ivan Bièche, Cindy Neuzillet   +5 more
openaire   +2 more sources

Surgical Treatment of Pancreatic Ductal Adenocarcinoma

Cancers, 2021
This special issue, “Surgical Treatment of Pancreatic Ductal Adenocarcinoma” contains 13 articles (five original articles, five reviews, and three systematic reviews/meta-analyses) authored by international leaders and surgeons who treat patients with ...
Kongyuan Wei, Thilo Hackert, Hackert Thilo   +2 more
exaly   +2 more sources

Pancreatic Ductal Adenocarcinoma and Its Variants

Surgical Pathology Clinics, 2016
Pancreatic cancer represents the seventh leading cause of cancer death in the world, responsible for more than 300,000 deaths per year. The most common tumor type among pancreatic cancers is pancreatic ductal adenocarcinoma, an infiltrating neoplasm with
Claudio Luchini, Paola Capelli, Aldo Scarpa   +2 more
exaly   +2 more sources