Results 51 to 60 of about 54,964 (316)

Pathomorphological feature of chronic pancreatitis (CP) is the development of pancreatic fibrosis with the accumulation of various collagen types, tubulin, fibronectin, laminin, and also intermediate filament proteins produced by activated pancreatic stel

Patologìâ, 2013
Pathomorphological feature of chronic pancreatitis (CP) is the development of pancreatic fibrosis with the accumulation of various collagen types, tubulin, fibronectin, laminin, and also intermediate filament proteins produced by activated pancreatic ...
T.V. Turovskaya, A.M. Gnilorybov, L.V. Vasilyeva, V.B. Kostogryz, M.S. Goncharuk   +4 more
doaj   +1 more source

Ansa pancreatica: a rare cause of acute reccurent pancreatitis

The Pan African Medical Journal, 2020
Acute pancreatitis is an inflammation of the pancreas that can be caused in rare situations by ansa pancretica, it is a rare anatomic variation of the pancreatic ducts.
Abdelilah El Bakouri, Othmane El Yamine, Mounir Bouali, Fatima Zahra Bensardi, Khalid El hattabi, Abdelaziz Fadil   +5 more
doaj   +1 more source

Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases

Frontiers in Veterinary Science, 2023
Vitamin D plays a role in anti-inflammatory processes, and the alteration of its metabolism is associated with the inflammatory processes of pancreatitis.
Dohee Lee, Sanggu Kim, Yoonhoi Koo, Yeon Chae, Juwon Wang, Soochong Kim, Taesik Yun, Mhan-Pyo Yang, Byeong-Teck Kang, Hakhyun Kim   +9 more
doaj   +1 more source

Management of an Accessory Bile Duct Leak Following Pancreaticoduodenectomy: A Novel Approach Utilizing a Percutaneous and Endoscopic Rendezvous. [PDF]

, 2017
Biliary leaks are uncommon but morbid complications of pancreaticoduodenectomies, which have historically been managed with percutaneous drainage, reoperation, or a combination of both. We report a de novo percutaneous-endoscopic hepaticojejunostomy from
Huang, Jason Y, Imagawa, David K, Lee, John G, Nelson, Kari J, Rapp, George A   +4 more
core   +1 more source

Severe fibrosis of the pancreas in chronic pancreatitis: main pathological components, immunophenotype of fibrogenic cells and collagen

Patologìâ, 2013
Pathomorphological feature of chronic pancreatitis (CP) is the development of pancreatic fibrosis with the accumulation of various collagen types, tubulin, fibronectin, laminin, and also intermediate filament proteins produced by activated pancreatic ...
V. О. Tumanskiy , I. S. Kovalenko
doaj   +1 more source

Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells. [PDF]

, 2000
Cell-cell and cell-matrix interactions play a critical role in tissue morphogenesis and in homeostasis of adult tissues. The integrin family of adhesion receptors regulates cellular interactions with the extracellular matrix, which provides three ...
Alpert, Bauer, Beattie, Beattie, Beattie, Blaschuk, Bosco, Brooks, Brooks, Calof, Cheng, Choquet, Cirulli, Cirulli, Cirulli, Clark, Clark, Dahl, DiPersio, Drake, Dudek, Ekblom, Felding-Habermann, Friedlander, George, Giancotti, Gu, Gu, Gullberg, Herrera, Herrera, Hynes, Hynes, Jaffe, Jansson, Jensen, Jones, Kantengwa, Langerhans, Langhofer, Like, Lin, Lombardi, Marchisio, Orci, Orci, Orci, Otonkoski, Otonkoski, Otonkoski, Pelletier, Pictet, Pictet, Pierschbacher, Ricordi, Rouiller, Sandler, Schwartz, Slack, Sonnenberg, Stefan, Strange, Talhouk, Teitelman, Tuch, Von Dorsche, Walker, Watt   +67 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Pancreatic Duct Glands Are Distinct Ductal Compartments That React to Chronic Injury and Mediate Shh-Induced Metaplasia [PDF]

, 2014
BACKGROUND & AIMS: Pancreatic intraepithelial neoplasia (PanIN) are pancreatic cancer precursor lesions of unclear origin and significance. PanIN aberrantly express sonic hedgehog (Shh), an initiator of pancreatic cancer, and gastrointestinal mucins.
Alsina, Janivette, Fernández–Del Castillo, Carlos, Lauwers, Gregory Y., Rakhlin, Elena Y., Rosow, David E., Strobel, Oliver, Thayer, Sarah P., Trainor, Amanda G., Warshaw, Andrew Louis   +8 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source