Results 101 to 110 of about 253,620 (220)

Vitamins and Chronic Wounds: How Altered Pharmacokinetics and Comorbidities Contribute to Vitamin Deficiencies

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Wound healing is complex and requires adequate amounts of macro‐ and micronutrients. When wound healing is delayed, a wound is considered chronic. Increasing evidence shows that vitamin deficiencies are prevalent in patients with chronic wounds, yet intervention studies with vitamin supplementation yielded inconsistent effects.
Michiel G. J. Balvers, Teuntje L. de Smit, Anne I. Slotegraaf, Remy H. H. Bemelmans, Joé L. P. Kolkert, Tim J. Schuijt, Renger F. Witkamp   +6 more
wiley   +1 more source

Pancreatic exocrine function in diabetes mellitus. Determination of fecal elastase [PDF]

, 2006
Background: One of the complications of diabetes mellitus is the development of pancreatic exocrine insufficiency. Aim: To study pancreatic exocrine function in diabetics patients.
Ledezma R., Rodrigo, Pineda Bravo, Pedro, Orellana N., Ivonne, Mancilla Asencio, Carla, Castillo Montecinos, Iván, Berger Fleiszig, Zoltán, Hurtado Heim, Carmen, Tobar Almonacid, Eduardo   +7 more
core  

Pancreatic Polypeptide in Parkinson’s Disease: A Potential Marker of Parasympathetic Denervation

Journal of Parkinson’s Disease, 2017
Background and objectives: Parkinson’s disease (PD) patients experience several non-motor symptoms from the gastrointestinal tract that may partly be caused by parasympathetic deficiency.
Karoline Knudsen, Bolette Hartmann, Tatyana D. Fedorova, Karen Østergaard, Klaus Krogh, Niels Møller, Jens J. Holst, Per Borghammer   +7 more
doaj   +1 more source

Exocrine dysfunction correlates with endocrinal impairment of pancreas in Type 2 diabetes mellitus

Indian Journal of Endocrinology and Metabolism, 2018
Background: Diabetes mellitus (DM) is a chronic abnormal metabolic condition, which manifests elevated blood sugar level over a prolonged period. The pancreatic endocrine system generally gets affected during diabetes, but often abnormal exocrine ...
H R Prasanna Kumar, H Basavana Gowdappa, Tejashwi Hosmani, Tejashri Urs   +3 more
doaj   +1 more source

Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways. [PDF]

Cell Metab, 2023
Basile G, Vetere A, Hu J, Ijaduola O, Zhang Y, Liu KC, Eltony AM, De Jesus DF, Fukuda K, Doherty G, Leech CA, Chepurny OG, Holz GG, Yun SH, Andersson O, Choudhary A, Wagner BK, Kulkarni RN.   +17 more
europepmc   +1 more source

Pancreatic secretory trypsin inhibitor stimulates the growth of rat pancreatic carcinoma cells [PDF]

, 1990
Pancreatic secretory trypsin inhibitor was examined for growth-promoting activity on five cell lines using standard cell culture techniques. One cell line, AR4-2J, derived from a rat pancreatic acinar cell carcinoma, responded with significantly ...
Curry, B J, Calam, J, Freeman, T C, Woodburn, J R   +3 more
core  

Trappin ovine molecule (TOM), the ovine ortholog of elafin, is an acute phase reactant in the lung [PDF]

, 2004
As large animal models continue to play an important role in translating lung-directed therapeutic strategies from laboratory animals to humans, there is an increasing interest in the analysis of endogenous regulators of inflammation at both a genomic ...
Collie, D David, Tate, Steven, Brown, Thomas I, Mistry, Rohit, Sallenave, Jean-Michel   +4 more
core   +1 more source

Lymphatic vessel remodeling and invasion in pancreatic cancer progressionResearch in context

EBioMedicine, 2019
Background: The lymphatic system is involved in metastasis in pancreatic cancer progression. In cancer staging, lymphatic spread has been used to assess the invasiveness of tumor cells.
Chia-Ning Shen, King-Siang Goh, Chi-Ruei Huang, Tsai-Chen Chiang, Chih-Yuan Lee, Yung-Ming Jeng, Shih-Jung Peng, Hung-Jen Chien, Mei-Hsin Chung, Ya-Hsien Chou, Chi-Che Hsieh, Subhash Kulkarni, Pankaj J. Pasricha, Yu-Wen Tien, Shiue-Cheng Tang   +14 more
doaj   +1 more source

A neutrophil mimicking metal-porphyrin-based nanodevice loaded with porcine pancreatic elastase for cancer therapy. [PDF]

Nat Commun, 2023
Cui T, Zhang Y, Qin G, Wei Y, Yang J, Huang Y, Ren J, Qu X.   +7 more
europepmc   +1 more source

[¹⁸F]Fluorothymidine Uptake in the Porcine Pancreatic Elastase-Induced Model of Abdominal Aortic Aneurysm. [PDF]

J Imaging, 2021
Gandhi R, Koch-Paszkowski J, Tsoumpas C, Bailey MA.   +3 more
europepmc   +1 more source