Results 81 to 90 of about 253,620 (220)

Shifts in amino acids profile in chronic pancreatitis.

open access: yesPLoS ONE
BackgroundChronic pancreatitis (CP) can lead to pancreatic exocrine insufficiency (PEI), causing protein malabsorption and altered amino acid levels.
Marko Malvik   +5 more
doaj   +1 more source

Challenges of drug resistance in the management of pancreatic cancer [PDF]

open access: yes, 2010
The current treatment of choice for metastatic pancreatic cancer involves single agent gemcitabine or combination of gemcitabine with capecitabine and erlotinib (tyrosine kinase inhibitor).
Naomi Walsh   +10 more
core   +1 more source

The Role of IL-6, 8, and 10, sTNFr, CRP, and Pancreatic Elastase in the Prediction of Systemic Complications in Patients with Acute Pancreatitis

open access: yesGastroenterology Research and Practice, 2013
Background and Aim. Early assessment of severity in acute pancreatitis (AP) is a key measure to provide rational and effective management. The aim of our study is to determine the prognostic value of interleukins (IL) 6, 8, and 10, soluble receptor for ...
E. Fisic   +5 more
doaj   +1 more source

Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao   +7 more
wiley   +1 more source

Diabetes and the risk of pancreatic cancer.

open access: yes, 1994
BACKGROUND: Diabetes and pancreatic cancer are known to be associated, but the cause of the association and whether diabetes is a risk factor for pancreatic cancer remain controversial.
Morselli Labate AM   +5 more
core   +1 more source

Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Immune‐cell dynamics in the tumor microenvironment converge on four major barriers to effective therapy: failed immune access, defective antigen visibility and priming, loss of effector maintenance, and suppressive tissue remodeling. These barriers emerge from local hypoxic, cytokine, metabolic, and stromal signals.
Pin Guo   +8 more
wiley   +1 more source

Laparoscopic pancreatic neck transection and double pancreatico-jejunostomy, an alternative surgical approach to chronic pancreatitis [PDF]

open access: yes, 2019
Chronic pancreatitis is a benign inflammatory process that results symptoms pertaining to loss of endocrine and exocrine function. Pain poses a great challenge in the management of CP and intractable pain represents the main indication for surgical ...
강창무, 이우정
core   +1 more source

Pancreatic endosonographic findings and clinical correlation in Crohn's disease

open access: yesClinics
OBJECTIVES: We aimed to evaluate the incidence of pancreatic alterations in Crohn's disease using endoscopic ultrasound (EUS) and to correlate the number of alterations with current clinical data.
Éverson Fernando Malluta   +8 more
doaj   +1 more source

Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu   +7 more
wiley   +1 more source

The Role of Bile in the Regulation of Exocrine Pancreatic Secretion [PDF]

open access: yes, 1992
As early as 1926 Mellanby (1) was able to show that introduction of bile into the duodenum of anesthetized cats produces a copious flow of pancreatic juice.
Riepl, Rudolf L., Lehnert, Peter
core   +1 more source

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