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Pancreatic Elastase 1 after Pancreatic Transplantation

Pancreas, 1991
Human pancreatic elastase 1 (E1) is a novel pancreas-specific proteinase that has not yet been investigated after pancreatic transplantation (PTx). Using a recently developed E1 ELISA, we studied the E1 serum curves in 36 type I diabetic patients subjected to PTx with enteric exocrine diversion from the pretransplant value up to 8 years after ...
R, Linder   +4 more
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Pancreatic Cationic Elastase in Porcine Experimental Pancreatitis

European Surgical Research, 1991
A radioimmunoassay for porcine, cationic, pancreatic elastase (irPE) is described. Normal porcine serum contains only small amounts of irPE (less than 3 micrograms/l). IrPE in serum and peritoneal exudate from 6 pigs with experimental pancreatitis was found mainly in a molecular form corresponding to free pro-enzyme.
H, Håkansson, A, Borgström, K, Ohlsson
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Human cationic, pancreatic elastase in acute pancreatitis

Scandinavian Journal of Clinical and Laboratory Investigation, 1993
Immunoreactive cationic pancreatic elastase (irPE) in serum and peritoneal exudate from 8 patients with severe acute pancreatitis was found mainly in complex with alpha-1-proteinase-inhibitor (alpha 1PI). Only minor amounts of irPE were found in a molecular form corresponding to the free proenzyme. The presence of alpha-2-macroglobulin (alpha 2M)-bound,
H O, Håkansson   +2 more
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Competitive inhibition of pancreatic elastase

Biochimica et Biophysica Acta (BBA) - Enzymology, 1973
Abstract N- Acetyl and N- carbobenzoxy derivatives of dipeptides of alanine, valine, leucine and isoleucine were found to be effective competitive inhibitors of the esterolytic activity of pancreatic elastase (EC 3.4.4.7) with K i values between 1 and 10 mM.
L, Dzialoszynski, T, Hofmann
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Pancreatic ductal cell carcinoma producing pancreatic elastase 1

Journal of Surgical Oncology, 1993
AbstractThe elevation of plasma pancreatic elastase 1 in patients with pancreatic cancer is caused by concomitant pancreatitis. There is no report that pancreatic ductal cell carcinoma tissue itself produced elastase 1. A 54‐year‐old woman underwent total pancreatectomy for pancreatic ductal cell carcinoma.
K, Iwase   +5 more
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Stabilization of Lyophilized Porcine Pancreatic Elastase

Pharmaceutical Research, 1993
Porcine pancreatic elastase, a well-characterized serine protease, has been used as a model to assess the effects of excessive humidity on solid-state stability of the lyophilized protein. Elastase lyophilized without excipients retained full activity immediately after freeze-drying but became denatured upon continued storage at 40 degrees C, 75 ...
B S, Chang, C S, Randall, Y S, Lee
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