Results 31 to 40 of about 19,681 (244)

Investigation of lipid digestion by fungal and porcine lipase supplements for severe pancreatic insufficiency using the in vitro dynamic TIM model

open access: yesBritish Journal of Pharmacy, 2023
Exocrine pancreatic insufficiency (EPI) is caused by insufficient secretion or limited activity of pancreatic enzymes, especially lipase. Chronic pancreatitis (CP) is the most common EPI disease.
Tânia Martins Garcia   +3 more
doaj   +1 more source

EXOCRINE PANCREATIC INSUFFICIENCY IN CHILDREN WITH TYPE 1 DIABETES MELLITUS: A NEW PROBLEM OF PEDIATRIC GASTROENTEROLOGY

open access: yesВопросы современной педиатрии, 2013
One of the complications of diabetes mellitus is the development of pancreatic exocrine insufficiency. Fecal elastase 1 is a good marker of pancreatic exocrine secretion.
A. A. Nizhevich   +4 more
doaj   +1 more source

Enzyme Replacement Therapy in the Pancreatic Duct Ligated Swine

open access: yesExperimental Biology and Medicine, 1972
SummaryPancreatic duct ligation (PDL) in swine reduced absorption of dietary fat and protein to less than 50%. Supplementation of the diet with pancreatin 4X NF at 0.1, 0.5 and 1.0% resulted in a significant improvement in fat absorption which approached normal on the highest level of pancreatin.
A R, Imondi, R P, Stradley, R, Wolgemuth
openaire   +2 more sources

Rational Prescribing of Pancreatic Enzymes for Patients with Pancreatic Cancer

open access: yesPharmacy
Most patients with pancreatic cancer at some point present with symptoms related to exocrine pancreatic insufficiency (EPI). These include diarrhea, abdominal bloating, indigestion, steatorrhea, weight loss, and anorexia.
Mary Acelle G. Garcia   +3 more
doaj   +1 more source

Exocrine Pancreatic Insufficiency in Diabetes Mellitus: Incidence, Pathogenesis, Diagnosis and Treatment

open access: yesGastroenterologìa, 2015
The article deals with exocrine pancreatic insufficiency (EPI), which is being detected in a significant number (30–50 %) of patients with diabetes mellitus (DM) type I and II and could potentially affect the compensation of DM.
S.M. Tkach
doaj   +1 more source

COMPARING THE ENZYME REPLACEMENT THERAPY COST IN POST PANCREATECTOMY PATIENTS DUE TO PANCREATIC TUMOR AND CHRONIC PANCREATITIS

open access: yesArquivos de Gastroenterologia
Background - Among late postoperative complications of pancreatectomy are the exocrine and endocrine pancreatic insufficiencies. The presence of exocrine pancreatic insufficiency imposes, as standard treatment, pancreatic enzyme replacement.
Anna Victoria FRAGOSO   +3 more
doaj   +1 more source

Pancreatic enzyme replacement therapy after gastric resection: An update [PDF]

open access: yesDigestive and Liver Disease, 2018
Exocrine pancreatic insufficiency (EPI) is one of the possible mechanisms of fat maldigestion following gastric surgery, together with reduced food intake, loss of gastric reservoir, small bowel bacterial overgrowth and rapid small bowel transit. Oral pancreatic enzyme replacement therapy (PERT) is the mainstay of treatment for EPI.
Filippo, Antonini   +4 more
openaire   +2 more sources

Neonatal diabetes mellitus – manifestation of GATA-6 syndrome [PDF]

open access: yesRomanian Journal of Pediatrics
GATA6 syndrome is an unusual genetic disorder that presents complications during pregnancy, congenital heart defects, neonatal diabetes, and severe pancreatic dysfunction.
Galina Gorbunov   +2 more
doaj   +1 more source

Pancreatic enzyme replacement therapy for young cystic fibrosis patients [PDF]

open access: yesJournal of Cystic Fibrosis, 2009
Maldigestion in cystic fibrosis (CF) affects approximately 90% of patients. As soon as pancreatic insufficiency is identified, enzyme supplementation is prescribed even with breast fed infants. A pancreatic enzyme preparation developed particularly for infants, Creon for children (CfC), contains smaller granules to be administered with a dosing spoon ...
Munck, Anne   +15 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy