Results 131 to 140 of about 880,817 (296)

Data on the inhibitory effect of endophytic fungi of traditional medicinal plants against pancreatic lipase (PL)

open access: yesData in Brief, 2019
This article describes isolation and pancreatic lipase (PL) inhibitory potential of 18 endophytic fungi isolated from the various parts of six indigenous medicinal plants.
Mohini P. Patil, Ravindra H. Patil
doaj   +1 more source

GLP‐1 receptor activation attenuates chronic migraine‐like behaviour: Sex‐specific modulation of opioid‐ and endocannabinoid‐related pathways

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Chronic migraine (CM) is a highly disabling condition that remains suboptimally treated. Metabolic disturbances may trigger migraine chronification, whereas impaired endogenous pain inhibition contributes to CM development. Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs), used for type 2 diabetes and obesity, show efficacy ...
Katarina Sićović   +6 more
wiley   +1 more source

Pancreatic Panniculitis as the First Presentation of Pancreatic Adenocarcinoma

open access: yes
JEADV Clinical Practice, EarlyView.
Claudine Howard‐James   +2 more
wiley   +1 more source

Autophagy Regulates Foxo1 Protein Abundance to Control Hepatic Glucose Production in Glucagon Signalling

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim During fasting, the liver undergoes coordinated metabolic adaptations to maintain systemic energy homeostasis. These adaptations are driven in part by glucagon, which promotes hepatic glucose production (HGP) and fatty acid oxidation (FAO) through mechanisms involving the transcription factor Foxo1.
Zheng Shen   +9 more
wiley   +1 more source

Investigating the inhibitory activity of green coffee and cacao bean extracts on pancreatic lipase

open access: yes, 2010
The present study investigated the effects of green coffee bean extract and Theobroma cacao bean extract on pancreatic lipase activity in vitro. Green coffee bean extract produced a J-shaped dose-dependent inhibition of pancreatic lipase with the ...
Almoosawi, Suzana   +9 more
core   +1 more source

Severe chronic neutrophilic cholangiohepatitis with massive choledocholithiasis and hepatolithiasis in a pony

open access: yesEquine Veterinary Education, EarlyView.
Summary A 20‐year‐old Camargue pony mare was referred for acute‐onset neurological signs and intermittent colic. Clinical examination revealed obtundation, cranial nerve deficits, head pressing, ventral strabismus and ataxia. Laboratory analyses showed marked hyperammonaemia, hyperbilirubinemia, severe increases in liver enzymes, hypoalbuminaemia and ...
C. Maino   +5 more
wiley   +1 more source

PANCREATIC LIPASE/COLIPASE BINDING SITE INVESTIGATION [PDF]

open access: yes
Pancreatic lipase is responsible for fat digestion in the intestine. The enzyme, which belongs to a special class of esterases, realizes an heterogeneous catalysis.
Granon, Simone   +4 more
core   +1 more source

Caracterização bioquímica de uma lipase recombinante de Staphylococus xylosus e detecção dos mecanismos estruturais envolvidos em sua termotolerância [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-graduação em Biotecnologia, Florianópolis, 2010As lipases são enzimas altamente versáteis que catalisam reações químicas com diversos ...
Bertoldo, Jean Borges
core  

Molecular dynamics simulations elucidate the misfolding mechanisms of secretion‐defective pancreatic lipase variants

open access: yesThe FEBS Journal, EarlyView.
Misfolding mutations in pancreatic lipase have been identified as potential contributors of chronic pancreatitis, an inflammatory disease of the human pancreas. Here, we describe the effect of these misfolding mutations on pancreatic lipase structure using molecular dynamics simulations and structural modeling.
Gyula Hoffka, András Szabó
wiley   +1 more source

Anti-obesity potential of selected tropical plants via pancreatic lipase inhibition

open access: yes, 2017
Natural products are a vast source of potential compounds that can be developed as anti-obesity agent. One of the mechanisms of anti-obesity agents is inhibition of pancreatic lipase. Assay of 24 crude extracts for their in vitro activity against porcine
Norsyuhada Alias   +5 more
semanticscholar   +1 more source

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