Results 171 to 180 of about 880,817 (296)

The Efferocytosis‐Driven Macrophage Polarization: A Concerto in the Tumor Immunosuppressive Microenvironment

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen   +3 more
wiley   +1 more source

Retatrutide‐Associated Improvements in Cardiovascular Risk Biomarkers in Adults With Obesity With or Without Type 2 Diabetes

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10183-10194, November 2026.
ABSTRACT Aims To further characterise the effects of retatrutide on cardiometabolic risk, lipoprotein and inflammatory biomarkers were assessed post hoc in phase 2 trials of adults with obesity/overweight with or without type 2 diabetes (T2D). Materials and Methods Data were analysed from two randomised, double‐blind, placebo‐controlled phase 2 trials.
Giacomo Ruotolo   +13 more
wiley   +1 more source

FAM3A Inhibits Plasma Triglyceride Levels via Microvasculature‐Involved Enhancement of VLDL‐Triglyceride Hydrolysis and Lipid Uptake

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
FAM3A enhances the PPARα signaling, leading to upregulated expression of lipid transporters including CD36 and TCF15. The upregulated CD36 and TCF15 enhance FA uptake and trans‐endothelial delivery in MVECs. Meanwhile, FAM3A‐enhanced PPARα signaling also increases LPL expression in myocytes and LPL position in lumen side of microvasculature to promote ...
Xiaohong Song   +7 more
wiley   +1 more source

A Portal‐Preorganized Cucurbit[7]uril‐Ruthenium Conjugate Enables Motif‐Selective Protein Sensing

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 44, 26 October 2026.
Reprogramming cucurbit[7]uril (CB7) recognition through portal engineering transforms an optically silent host into a motif‐selective photoluminescent receptor. The portal‐preorganized CB7‐Rubpy conjugate directly reports changes in aromatic motif accessibility, enabling optical sensing of protein misfolding and refolding.
Patrick Gruhs   +10 more
wiley   +1 more source

Interfacial and Molecular Mechanisms of Pancreatic Lipase Modulation by Saponin-Rich Extracts with Antioxidant Activity. [PDF]

open access: yesMolecules
Sroka Z   +10 more
europepmc   +1 more source

Serial measurement of serum pancreatic lipase immunoreactivity and trypsin-like immunoreactivity concentrations in cats with chronic enteropathy. [PDF]

open access: yesJ Feline Med Surg
Karra DA   +7 more
europepmc   +1 more source

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