Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen +3 more
wiley +1 more source
ABSTRACT Aims To further characterise the effects of retatrutide on cardiometabolic risk, lipoprotein and inflammatory biomarkers were assessed post hoc in phase 2 trials of adults with obesity/overweight with or without type 2 diabetes (T2D). Materials and Methods Data were analysed from two randomised, double‐blind, placebo‐controlled phase 2 trials.
Giacomo Ruotolo +13 more
wiley +1 more source
FAM3A enhances the PPARα signaling, leading to upregulated expression of lipid transporters including CD36 and TCF15. The upregulated CD36 and TCF15 enhance FA uptake and trans‐endothelial delivery in MVECs. Meanwhile, FAM3A‐enhanced PPARα signaling also increases LPL expression in myocytes and LPL position in lumen side of microvasculature to promote ...
Xiaohong Song +7 more
wiley +1 more source
A Portal‐Preorganized Cucurbit[7]uril‐Ruthenium Conjugate Enables Motif‐Selective Protein Sensing
Reprogramming cucurbit[7]uril (CB7) recognition through portal engineering transforms an optically silent host into a motif‐selective photoluminescent receptor. The portal‐preorganized CB7‐Rubpy conjugate directly reports changes in aromatic motif accessibility, enabling optical sensing of protein misfolding and refolding.
Patrick Gruhs +10 more
wiley +1 more source
Longitudinal comparison of serum pancreatic lipase activity and pancreatic lipase immunoreactivity with clinical signs in cats with suspicion of pancreatitis. [PDF]
Kook PH.
europepmc +1 more source
Interfacial and Molecular Mechanisms of Pancreatic Lipase Modulation by Saponin-Rich Extracts with Antioxidant Activity. [PDF]
Sroka Z +10 more
europepmc +1 more source
Serial measurement of serum pancreatic lipase immunoreactivity and trypsin-like immunoreactivity concentrations in cats with chronic enteropathy. [PDF]
Karra DA +7 more
europepmc +1 more source
Discovery of Pancreatic Lipase Inhibitory and Antimicrobial Constituents in Crataegi Folium by High-Performance Thin-Layer Chromatography-Bioautography-Mass Spectrometry. [PDF]
Zhu L +7 more
europepmc +1 more source
Mechanistic Insights into Pancreatic Lipase Inhibition by Sugarcane Polyphenols: A Structural and Kinetic Study. [PDF]
Liu Q, Wang PP, Fu X, Chen C.
europepmc +1 more source
Non-pancreatic Lipase in Children with Pancreatic Fibrosis [PDF]
C A, ROSS, H G, SAMMONS
openaire +2 more sources

