Results 1 to 10 of about 1,063,041 (329)

High-resolution Hi-C maps highlight multiscale 3D epigenome reprogramming during pancreatic cancer metastasis

open access: yesJournal of Hematology & Oncology, 2021
Background Pancreatic cancer’s poor prognosis is caused by distal metastasis, which is associated with epigenetic changes. However, the role of the 3D epigenome in pancreatic cancer biology, especially its metastasis, remains unclear.
Bo Ren   +10 more
doaj   +2 more sources

Isolated Pancreatic Metastasis from a Lung Adenocarcinoma Primary: A Case Report and Literature Review [PDF]

open access: yesCase Reports in Oncology, 2023
Isolated pancreatic metastasis is a rare occurrence and is commonly misdiagnosed as primary pancreatic malignancy. We present a case of a 65-year-old female patient with a history of stage IIIA lung adenocarcinoma, who developed significant epigastric ...
Ogheneyoma Akpoviroro   +2 more
doaj   +2 more sources

Successful resection of pancreatic metastasis from oesophageal squamous cell carcinoma: a case report and review of the literature

open access: yesBMC Cancer, 2019
Background Oesophageal cancer has a high metastatic potential and poor prognosis, with a significant risk of recurrence after radical resection. However, resected pancreatic metastasis from oesophageal cancer is rare. Case presentation Eleven years prior,
Wataru Koizumi   +10 more
doaj   +2 more sources

Small extracellular vesicles: from mediating cancer cell metastasis to therapeutic value in pancreatic cancer

open access: yesCell Communication and Signaling, 2022
Pancreatic cancer is a highly malignant tumor and, is extremely difficult to diagnose and treat. Metastasis is one of the critical steps in the development of cancer and uses cell to cell communication to mediate changes in the microenvironment.
Wenjie Zhang   +7 more
doaj   +2 more sources

Molecular mechanisms of pancreatic cancer liver metastasis: the role of PAK2

open access: yesFrontiers in Immunology
BackgroundPancreatic cancer remains an extremely malignant digestive tract tumor, posing a significant global public health burden. Patients with pancreatic cancer, once metastasis occurs, lose all hope of cure, and prognosis is extremely poor.
Hao Yang   +9 more
doaj   +2 more sources

Targeted intervention of eIF4A1 inhibits EMT and metastasis of pancreatic cancer cells via c-MYC/miR-9 signaling

open access: yesCancer Cell International, 2021
Background Owing to the lack of effective treatment options, early metastasis remains the major cause of pancreatic ductal adenocarcinoma (PDAC) recurrence and mortality. However, the molecular mechanism of early metastasis is largely unknown.
Yuchong Zhao   +8 more
doaj   +2 more sources

Solitary pancreatic metastasis of extremity myxoid liposarcoma: a case report and literature review

open access: yesBMC Cancer, 2018
Background Myxoid liposarcoma has a distinct migration aptitude; however, pancreatic metastasis is rare. Case presentation We report on the case of a 40-year-old female patient who suffered solitary pancreatic metastasis of myxoid liposarcoma and had a ...
Dingding Wang   +4 more
doaj   +2 more sources

Tumor microenvironment participates in metastasis of pancreatic cancer

open access: yesMolecular Cancer, 2018
Pancreatic cancer is a deadly disease with high mortality due to difficulties in its early diagnosis and metastasis. The tumor microenvironment induced by interactions between pancreatic epithelial/cancer cells and stromal cells is critical for ...
Bo Ren   +6 more
doaj   +2 more sources

Pancreatic Metastasis From a Vulvar Melanoma Diagnosed by Endoscopic Ultrasound-Guided Fine-Needle Biopsy. [PDF]

open access: diamondACG Case Rep J
Almeida R   +5 more
europepmc   +2 more sources

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