Results 141 to 150 of about 240,816 (350)

A Long Non-coding RNA Signature to Improve Prognostic Prediction of Pancreatic Ductal Adenocarcinoma

Frontiers in Oncology, 2019
Background: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive solid malignant tumors worldwide. Increasing investigations demonstrate that long non-coding RNAs (lncRNAs) expression is abnormally dysregulated in cancers.
Chenhao Zhou, Shun Wang, Qiang Zhou, Jin Zhao, Xianghou Xia, Wanyong Chen, Wanyong Chen, Yan Zheng, Min Xue, Feng Yang, Deliang Fu, Yirui Yin, Manar Atyah, Lunxiu Qin, Lunxiu Qin, Yue Zhao, Christiane Bruns, Huliang Jia, Ning Ren, Ning Ren, Qiongzhu Dong, Qiongzhu Dong   +21 more
doaj   +1 more source

Herbal Formula Yi‐Fei‐Jie‐Du‐Tang Regulates Epithelial‐Mesenchymal Transition and Vasculogenic Mimicry in Lung Cancer via HIF1A‐Mediated Ferroptosis

Advanced Biology, Volume 9, Issue 3, March 2025.
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang, Die Yang, Chengjia Yuan, Yang Wu, Qingying Wang, Yongjian Wu, Xiaochun Zhang   +6 more
wiley   +1 more source

Inhibition of Liver Metastasis of Human Pancreatic Carcinoma by Angiogenesis Inhibitor TNP‐470 in Combination with Cisplatin [PDF]

, 1998
Takayuki Shishido, Takahiro Yasoshima, Ryuichi Denno, Mitsuhiro Mukaiya, Noriyuki Sato, Koichi Hirata   +5 more
openalex   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Probing Early Particle‐Cell Membrane Interactions via Single‐Cell and Single‐Particle Interaction Analysis

Advanced Functional Materials, EarlyView.
The pre‐internalization phase of endocytosis remains poorly characterized at single‐cell levels. Single‐cell pre‐internalization mechanics are investigated using advanced robotic techniques. Cancer cells exhibit biphasic adhesion – rapid initial binding followed by reinforcement – while fibroblasts show gradual engagement.
Houari Bettahar, Christos Tapeinos, Oğulcan Işıtman, Carmine D'Amico, Alexandra Correia, Hélder A. Santos, Quan Zhou   +6 more
wiley   +1 more source

Radiotherapy-induced cell death activates paracrine HMGB1-TLR2 signaling and accelerates pancreatic carcinoma metastasis

Journal of Experimental & Clinical Cancer Research, 2018
Background Dying cells after irradiation could promote the repopulation of surviving cancer cells leading to tumor recurrence. We aim to define the role of dying cells in promoting pancreatic cancer cells metastasis following radiotherapy.
Xuelian Chen, Lirong Zhang, Yujie Jiang, Lian Song, Yanfang Liu, Fang Cheng, Xin Fan, Xiongfeng Cao, Aihua Gong, Dongqing Wang, Haitao Zhu   +10 more
doaj   +1 more source

Effect of Angiostatin on Liver Metastasis of Pancreatic Cancer in Hamsters [PDF]

, 2000
Ken Yanagi, Masahiko Onda, Eiji Uchida
openalex   +1 more source

Generalizable Pancreas Segmentation via a Dual Self-Supervised Learning Framework [PDF]

Recently, numerous pancreas segmentation methods have achieved promising performance on local single-source datasets. However, these methods don't adequately account for generalizability issues, and hence typically show limited performance and low stability on test data from other sources.
arxiv   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Detection of Peri-Pancreatic Edema using Deep Learning and Radiomics Techniques [PDF]

arXiv
Identifying peri-pancreatic edema is a pivotal indicator for identifying disease progression and prognosis, emphasizing the critical need for accurate detection and assessment in pancreatitis diagnosis and management. This study \textit{introduces a novel CT dataset sourced from 255 patients with pancreatic diseases, featuring annotated pancreas ...
arxiv