Results 141 to 150 of about 273,218 (326)

Deep Learning How to Fit an Intravoxel Incoherent Motion Model to Diffusion-Weighted MRI

, 2019
Purpose: This prospective clinical study assesses the feasibility of training a deep neural network (DNN) for intravoxel incoherent motion (IVIM) model fitting to diffusion-weighted magnetic resonance imaging (DW-MRI) data and evaluates its performance ...
Barbieri, Sebastiano, Gurney-Champion, Oliver J., Klaassen, Remy, Thoeny, Harriet C.   +3 more
core   +1 more source

Risk Assessment of Liver Metastasis in Pancreatic Cancer Patients Using Multiple Models Based on Machine Learning: A Large Population-Based Study [PDF]

, 2022
Qinggang Li, Lu Bai, Jiyuan Xing, Xiaorui Liu, Dan Liu, Xiaobo Hu   +5 more
openalex   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

From the anal canal to the pancreas: diagnostic challenges of radiologic surveillance in detecting rare but potentially curable metastases — a case report

Frontiers in Oncology
IntroductionPancreatic metastases from anal canal squamous cell carcinoma (SCC) are exceptionally rare. To date, only one previous case has been reported.
Jelena Stanić, Jelena Stanić, Ivana Šović, Luka Jovanović, Predrag Nikić, Predrag Nikić, Tatjana Arsenijević, Tatjana Arsenijević   +7 more
doaj   +1 more source

Additional file 10 of Upregulation of METTL14 mediates the elevation of PERP mRNA N6 adenosine methylation promoting the growth and metastasis of pancreatic cancer

, 2020
Min Wang, Jun Liu, Yan Zhao, Ruizhi He, Xiaodong Xu, Xingjun Guo, Xu Li, Simiao Xu, Ji Miao, Jianpin Guo, Hang Zhang, Jun Gong, Feng Zhu, Rui Tian, Chengjian Shi, Feng Peng, Yechen Feng, Shuo Yu, Yu Xie, Jianxin Jiang, Min Li, Wenyi Wei, Chuan He, Renyi Qin   +23 more
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Pancreatic metastases from urothelial cancer

European Journal of Case Reports in Internal Medicine
Background: Urothelial carcinoma (UC) is a common malignancy that rarely metastasizes to the pancreas. Pancreatic masses in patients with UC present significant diagnostic challenges.
Maria Kyrkasiadou, Ioannis S. Papanikolaou, Ekaterini Politi, Vasiliki Nikolaidou, Konstantina Kakogianni, Keisi Mara, Aristotle Bamias   +6 more
doaj   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Identification of integrin drug targets for 17 solid tumor types. [PDF]

, 2018
Integrins are contributors to remodeling of the extracellular matrix and cell migration. Integrins participate in the assembly of the actin cytoskeleton, regulate growth factor signaling pathways, cell proliferation, and control cell motility.
Arun, Adith S, Lam, Kit S, Tepper, Clifford G   +2 more
core   +1 more source

Reduced expression of the H19 long non-coding RNA inhibits pancreatic cancer metastasis [PDF]

, 2018
Hisashi Yoshimura, Yoko Matsuda, Masami Yamamoto, Masaki Michishita, Kimimasa Takahashi, Norihiko Sasaki, Naoshi Ishikawa, Junko Aida, Kaiyo Takubo, Tomio Arai, Toshiyuki Ishiwata   +10 more
openalex   +1 more source