Results 181 to 190 of about 273,218 (326)

Supplementary Figure from Targeting Treg-Expressed STAT3 Enhances NK-Mediated Surveillance of Metastasis and Improves Therapeutic Response in Pancreatic Adenocarcinoma

, 2023
Miles Piper, Benjamin Van Court, Adam C. Mueller, Shuichi Watanabe, Thomas E. Bickett, Shilpa Bhatia, Laurel B. Darragh, Max Mayeda, Diemmy Nguyen, Jacob Gadwa, Michael W. Knitz, Sophia Corbo, Rustain Morgan, Jung‐Jae Lee, Alexander L. Dent, Karyn A. Goodman, Wells A. Messersmith, Richard D. Schulick, Marco Del Chiaro, Yuwen Zhu, Ross M. Kedl, Laurel Lenz, Sana D. Karam   +22 more
openalex   +1 more source

Inhibition of Mitochondrial Redox Signaling with MitoQ Prevents Metastasis of Human Pancreatic Cancer in Mice [PDF]

, 2022
Tânia Capelôa, Justine A. Van de Velde, Donatienne d’Hose, Sara Lipari, Françoise Derouane, Loïc Hamelin, Marie Bedin, Thibaut Vazeille, François P. Duhoux, Michael P. Murphy, Paolo E. Porporato, Bernard Gallez, Pierre Sonveaux   +12 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source

Pancreatic metastasis from papillary thyroid cancer: a case report and literature review. [PDF]

Korean J Clin Oncol, 2023
Song SH, Hur YH, Cho CK, Koh YS, Park EK, Kim HJ, Shin SH, Yu SY, Oh CY.   +8 more
europepmc   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Early progression of a pancreatic metastasis of synovial sarcoma after pancreatectomy. [PDF]

Surg Case Rep, 2023
Okazaki M, Katano K, Sugita H, Tokoro T, Gabata R, Takada S, Nakanuma S, Makino I, Yagi S.   +8 more
europepmc   +1 more source

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

Advanced Science, EarlyView.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen, Zhihang Xu, Yiping Zou, Zhenlai Jiang, Yecheng Li, Taochen He, Hanlin Yin, Jiali Li, Yanfei An, Jiande Han, Yuqi Xie, Wei Gan, Yaolin Xu, Wenquan Wang, Junyi He, Haibo Wang, Wenchuan Wu, Zhenyu Ye, Wenhui Lou, Jihui Hao, Liang Liu, Jun Yu, Ning Pu   +22 more
wiley   +1 more source

A pancreatic metastasis of anaplastic thyroid carcinoma: a rare case report. [PDF]

Ann Med Surg (Lond), 2023
Zarg El Ayoun R, Chtourou MF, Beji H, Kchaou M, Belfekih H, Chelbi E, Mighri MM, Touinsi H.   +7 more
europepmc   +1 more source

Pancreatic metastasis of a pleuropulmonary blastoma in an adult

, 2000
Thorsten Walles, Omke E. Teebken, M. Bartels, J. Fangmann, G. F. W. Scheumann, Maximilian Pichlmaier, J Klempnauer   +6 more
openalex   +1 more source