Advanced Science, EarlyView.A hollow nanomotor (PM‐HMSN/Arg) propelled by ultrasound‐triggered nitric oxide (NO) was developed. The nanomotor employs a “tethering‐relaxing‐drilling” mechanism to overcome biological barriers, enabling multimodal theranostics of cancer with deep penetration and extended lifetime.
Xue Xu +7 more
wiley +1 more source
Pancreatic metastasis of Merkel cell carcinoma and concomitant insulinoma: Case report and literature review [PDF]
, 2005 Jeannine Bachmann +6 more
openalex +1 more source
Cross-Organ Domain Adaptive Neural Network for Pancreatic Endoscopic Ultrasound Image Segmentation [PDF]
arXivAccurate segmentation of lesions in pancreatic endoscopic ultrasound (EUS) images is crucial for effective diagnosis and treatment. However, the collection of enough crisp EUS images for effective diagnosis is arduous. Recently, domain adaptation (DA) has been employed to address these challenges by leveraging related knowledge from other domains. Most
arxiv
Recent Advances in mRNA Delivery Systems for Cancer Therapy
Advanced Science, EarlyView.This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang +9 more
wiley +1 more source
A Case Report on Rare Case of Pancreatic Metastasis from Primary Lung Adenocarcinoma: Treated Through a Non-surgical Approach. [PDF]
J Cancer Allied Spec, 2023 Raza SM, Riaz A, Shahid A, Sadaf T.
europepmc +1 more source
In Silico Pharmacokinetic and Molecular Docking Studies of Natural Plants against Essential Protein KRAS for Treatment of Pancreatic Cancer [PDF]
arXivA kind of pancreatic cancer called Pancreatic Ductal Adenocarcinoma (PDAC) is anticipated to be one of the main causes of mortality during past years. Evidence from several researches supported the concept that the oncogenic KRAS (Ki-ras2 Kirsten rat sarcoma viral oncogene) mutation is the major cause of pancreatic cancer. KRAS acts as an on-off switch
arxiv
Advanced Science, EarlyView.SCORT–Cas13d–pre‐gHoxB13 lipid nanoparticles precisely deliver Cas13d mRNA and guide RNAs to metastatic prostate tumors in the liver, knocking down the “undruggable” transcription factor HoxB13. This approach suppresses metastatic tumor growth, extends mouse survival, and does not induce major organ toxicity or immune activation, offering a safe and ...
Zhifen Cui +15 more
wiley +1 more source
Distant organ metastasis patterns in lung cancer patients with pancreatic metastasis - a cluster analysis. [PDF]
Contemp Oncol (Pozn), 2022 Okauchi S +4 more
europepmc +1 more source
Advanced Science, EarlyView.The study develops engineered exosomes (EmDEX@GA) for locoregional immunomodulation of tumor‐draining lymph node (TDLN). EmDEX@GA can actively target to TDLN and remodel its immunosuppressive microenvironment through the synergistic effects of PD‐1/PD‐L1 blockade and STING pathway activation, subsequently enhance anti‐tumor immunity and suppress tumor ...
Yizhen Wang +12 more
wiley +1 more source
Case Report: Pancreatic metastasis of renal cell carcinoma 16 years after nephrectomy. [PDF]
Front Oncol, 2023 Lou Y, Guo K, Zheng S.
europepmc +1 more source