Results 211 to 220 of about 240,816 (350)

Case Report of a Pancreatic and Gallbladder Metastasis from Renal Cell Carcinoma 17 Years after a Nephrectomy

, 2003
Kazuhisa Shirai, Shinji FUKATA, Tadashi Ito, Ryuzo Yamaguchi, Hiroo Mukaiyama, Michihiko Narita   +5 more
openalex   +2 more sources

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

Advanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang, Kexin He, Ruixue Huo, Weihan Li, Shan Zhang, Lu‐Ju Jiang, Hao Wu, Minhao Yu, Shu‐Heng Jiang, Junli Xue   +9 more
wiley   +1 more source

A pancreatic metastasis from a colon carcinoma mimicking a primary tumor diagnosed by EUS-guided fine-needle biopsy. [PDF]

Endosc Ultrasound, 2023
Rizza S, Maldi E, Laudi C, Mellano A, Pisacane A, Staiano T.   +5 more
europepmc   +1 more source

Inhibition of STAT3Tyr705 Phosphorylation by Smad4 Suppresses Transforming Growth Factor β–Mediated Invasion and Metastasis in Pancreatic Cancer Cells [PDF]

, 2008
Shujie Zhao, Kolaparthi Venkatasubbarao, Jillian W. Lazor, Jane Sperry, Xin Jin, Lin Cao, James W. Freeman   +6 more
openalex   +1 more source

Sortilin‐Mediated Rapid, Precise and Sustained Degradation of Membrane Proteins via mRNA‐Encoded Lysosome‐Targeting Chimera

Advanced Science, EarlyView.
The study identified sortilin as a promising LTR, enabling targeted degradation of oncogenic proteins through an mRNA‐encoded MedTAC strategy. In a mouse model, MedTACPTK7 reduced PTK7 by up to 80%, extended survival, and showed excellent pharmacokinetics without toxicity, providing a scalable platform for targeted therapies.
Xin Chang, Xinyu Qiu, Xiaoning Tong, Shaoju Gan, Weicheng Yi, Sitao Xie, Xiangsheng Liu, Chao Zuo, Weihong Tan   +8 more
wiley   +1 more source

A rare case of pancreatic metastasis of lung adenocarcinoma. [PDF]

Oxf Med Case Reports, 2021
Yehouenou Tessi RT, Jerguigue H, Latib R, Omor Y.   +3 more
europepmc   +1 more source

A Resectable Case of Solitary Pancreatic Metastasis from Rectal Cancer

, 2004
Hitoshi Inagaki, Takanori Matsui, Hiroshi Kojima, Junji Kato, Taiki Kojima, Yasunobu Fujimitsu, Tsuyoshi Kurokawa, Junichi Sakamoto, Toshiaki Nonami   +8 more
openalex   +2 more sources

Inducible re-expression of p16 in an orthotopic mouse model of pancreatic cancer inhibits lymphangiogenesis and lymphatic metastasis [PDF]

, 2008
Petra Schulz, A Scholz, Annett Rexin, Peter Hauff, Michael Schirner, Bertram Wiedenmann, Katharina Detjen   +6 more
openalex   +1 more source

PP1A Modulates the Efficacy of Lenvatinib Plus ICIs Therapy by Inhibiting Ferroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
PP1A dephosphorylates Keap1 at the S104 site, stabilizing and promoting the nuclear translocation of Nrf2, which upregulates the expression of antioxidant genes and PD‐L1. This leads to suppressed ferroptosis and enhanced immune evasion, thereby improving the efficacy of TKI and ICI combination therapy.
Jitong Zhou, Meng Gao, Shikun Zhang, Wing‐Wa Guo, Wenzhi He, Minghe Zhang, Xi Chen, Cairang Dongzhi, Xiaomian Li, Yufeng Yuan, Weijie Ma   +10 more
wiley   +1 more source

Whole-Body MRI Showing Unusual Pancreatic Metastasis from a Forearm Rhabdomyosarcoma without Lung Involvement. [PDF]

Turk Arch Pediatr, 2022
Ayaz E, Gündoğdu F, Gedikoğlu G, Aydıngöz Ü.   +3 more
europepmc   +1 more source