Results 221 to 230 of about 240,816 (350)

Colorectal Cancer Cells–Derived Exosomal PIK3CA Mutation DNA Promotes Tumor Metastasis by Activating Fibroblast and Affecting Tumor Metastatic Microenvironment

open access: yesAdvanced Science, EarlyView.
PIK3CAH1047R DNA in colorectal cancer (CRC) cell‐derived exosomes can be delivered into recipient fibroblasts, where it is transcribed and translated, leading to the activation of fibroblasts into cancer‐associated fibroblasts, which secrete elevated levels of IL6. The simultaneous detection and targeting of PIK3CAH1047R mutation and IL6 may serve as a
Rui Wang   +6 more
wiley   +1 more source

Solitary pancreatic metastasis from squamous cell lung carcinoma: A case report and review of literature. [PDF]

open access: yesWorld J Gastrointest Endosc, 2022
Rais K   +8 more
europepmc   +1 more source

A CASE OF MAMMARY GLAND METASTASIS OF PANCREATIC CANCER

open access: bronze, 2004
Shigeyuki Hojo   +5 more
openalex   +2 more sources

Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple‐Negative Breast Cancer Models

open access: yesAdvanced Science, EarlyView.
Novel ATR/PARP1 dual inhibitors are developed for the first time. Advanced lead B8 effectively reduces cell viability in vitro and suppresses tumor growth in vivo, with better potency than ATRi and PARPi alone or in combination. Mechanistically, B8 induces apoptosis, arrests the cell cycle, and inhibits cancer cells colony formation, migration, and ...
Yuan Gao   +13 more
wiley   +1 more source

Repeat pancreatic resection for metachronous pancreatic metastasis from renal cell carcinoma: A case report. [PDF]

open access: yesInt J Surg Case Rep, 2022
Itamoto S   +5 more
europepmc   +1 more source

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

open access: yesAdvanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen   +9 more
wiley   +1 more source

A case of an ectopic Pacinian corpuscle in the pancreas mimicking pancreatic metastasis of renal cell carcinoma. [PDF]

open access: yesNagoya J Med Sci
Ogawa H   +7 more
europepmc   +1 more source

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